Publications by authors named "Patrick Pollard"

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Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes.
Julie Adam, Reshma Ramracheya, Margarita V Chibalina, Nicola Ternette, Alexander Hamilton, Patrick J Pollard

Cell Rep· September 2017

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Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.
Amelie V Guitart, Theano I Panagopoulou, Arnaud Villacreces, Milica Vukovic, Catarina Sepulveda, Patrick J Pollard

J Exp Med· March 2017

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Expression of Idh1 in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis.
Chiara Bardella, Osama Al-Dalahmah, Daniel Krell, Pijus Brazauskas, Khalid Al-Qahtani, Patrick J Pollard

Cancer Cell· October 2016

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Current morphologic criteria perform poorly in identifying hereditary leiomyomatosis and renal cell carcinoma syndrome-associated uterine leiomyomas.
Sana Alsolami, Mona El-Bahrawy, Steve E Kalloger, Nagla AlDaoud, Tilak B Pathak, Patrick J Pollard

Int J Gynecol Pathol· November 2014

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Rewiring mitochondrial pyruvate metabolism: switching off the light in cancer cells?
Peter W Szlosarek, SukJun Lee, Patrick J Pollard

Mol Cell· November 2014

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Telomerase reverse transcriptase promoter mutations in tumors originating from the adrenal gland and extra-adrenal paraganglia.
Thomas G Papathomas, Lindsey Oudijk, Ellen C Zwarthoff, Edward Post, Floor A Duijkers, Patrick J Pollard

Endocr Relat Cancer· August 2014

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The Succinated Proteome of FH-Mutant Tumours.
Ming Yang, Nicola Ternette, Huizhong Su, Raliat Dabiri, Benedikt M Kessler, Patrick J Pollard

Metabolites· August 2014

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Prolyl hydroxylase domain enzymes: important regulators of cancer metabolism.
Ming Yang, Huizhong Su, Tomoyoshi Soga, Kamil R Kranc, Patrick J Pollard

Hypoxia (Auckl)· August 2014

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Concise review: genetic dissection of hypoxia signaling pathways in normal and leukemic stem cells.
Deniz Gezer, Milica Vukovic, Tomoyoshi Soga, Patrick J Pollard, Kamil R Kranc

Stem Cells· June 2014

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Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas.
Luis Jaime Castro-Vega, Alexandre Buffet, Aguirre A De Cubas, Alberto Cascón, Mélanie Menara, Patrick J Pollard

Hum Mol Genet· May 2014

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OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.
Rachelle S Singleton, Phebee Liu-Yi, Fabio Formenti, Wei Ge, Rok Sekirnik, Patrick J Pollard

Proc Natl Acad Sci U S A· March 2014

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Renal cell carcinoma: translational aspects of metabolism and therapeutic consequences.
Oscar C Y Yang, Patrick H Maxwell, Patrick J Pollard

Kidney Int· October 2013

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Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance.
Amelie V Guitart, Chithra Subramani, Alejandro Armesilla-Diaz, Gillian Smith, Catarina Sepulveda, Patrick Pollard

Blood· September 2013

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Oncometabolites: linking altered metabolism with cancer.
Ming Yang, Tomoyoshi Soga, Patrick J Pollard

J Clin Invest· September 2013

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Succinate: a new epigenetic hacker.
Ming Yang, Patrick J Pollard

Cancer Cell· June 2013

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A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia.
Julie Adam, Ming Yang, Christina Bauerschmidt, Mitsuhiro Kitagawa, Linda O'Flaherty, Patrick J Pollard

Cell Rep· May 2013

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Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.
Nicola Ternette, Ming Yang, Mahima Laroyia, Mitsuhiro Kitagawa, Linda O'Flaherty, Patrick J Pollard

Cell Rep· March 2013

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Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.
Ruo-Li Chen, Simon Nagel, Michalis Papadakis, Tammie Bishop, Patrick Pollard

J Physiol· August 2012

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Cells lacking the fumarase tumor suppressor are protected from apoptosis through a hypoxia-inducible factor-independent, AMPK-dependent mechanism.
Chiara Bardella, Martina Olivero, Annalisa Lorenzato, Massimo Geuna, Julie Adam, Patrick J Pollard

Mol Cell Biol· August 2012

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The emerging role of fumarate as an oncometabolite.
Ming Yang, Tomoyoshi Soga, Patrick J Pollard, Julie Adam

Front Oncol· August 2012

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Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.
Houman Ashrafian, Gabor Czibik, Mohamed Bellahcene, Dunja Aksentijević, Anthony C Smith, Patrick J Pollard

Cell Metab· March 2012

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The C-terminus of Apc does not influence intestinal adenoma development or progression.
Annabelle Lewis, Hayley Davis, Maesha Deheragoda, Patrick Pollard, Emma Nye

J Pathol· January 2012

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Novel insights into FH-associated disease are KEAPing the lid on oncogenic HIF signalling.
Julie Adam, Peter J Ratcliffe, Patrick J Pollard

Oncotarget· November 2011

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Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Julie Adam, Emine Hatipoglu, Linda O'Flaherty, Nicola Ternette, Natasha Sahgal, Patrick J Pollard

Cancer Cell· October 2011

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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
Christian Frezza, Liang Zheng, Ori Folger, Kartik N Rajagopalan, Elaine D MacKenzie, Patrick J Pollard

Nature· August 2011

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