Publications by authors named "Peter Cornelius"

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A Phase 1 Safety Study of Evexomostat (SDX-7320) in Patients with Late-Stage Cancer: An Antiangiogenic, Insulin-Sensitizing Drug Conjugate Targeting METAP2.
Monica M Mita, Alain C Mita, Bradley J Carver, James M Shanahan, Benjamin A Mayes, Peter Cornelius

Cancer Res Commun· June 2025

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Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and Anti-metastatic Activity.
Peter Cornelius, Benjamin A Mayes, John S Petersen, David J Turnquist, Pierre J Dufour

Mol Cancer Ther· May 2024

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Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor.
Kim F McClure, Margaret Jackson, Kimberly O Cameron, Daniel W Kung, David A Perry, Peter Cornelius

Bioorg Med Chem Lett· October 2013

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Cosmetic Tattooing of Free Flaps following Head and Neck Reconstruction.
Martin D Batstone, Carly M Fox, Mary E Dingley, C Peter Cornelius

Craniomaxillofac Trauma Reconstr· March 2013

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From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptor.
Kentaro Futatsugi, Vincent Mascitti, Cristiano R W Guimarães, Nao Morishita, Cuiman Cai, Peter Cornelius

Bioorg Med Chem Lett· January 2013

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Design and synthesis of diazatricyclodecane agonists of the G-protein-coupled receptor 119.
Etzer Darout, Ralph P Robinson, Kim F McClure, Matthew Corbett, Bryan Li, Peter Cornelius

J Med Chem· January 2013

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Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor.
Michael Fichtner, Eunsun Lee, Elizabeth Tomlinson, Dennis Scott, Peter Cornelius

Bioorg Med Chem Lett· April 2012

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Oxidative metabolism of a quinoxaline derivative by xanthine oxidase in rodent plasma.
Raman Sharma, Heather Eng, Gregory S Walker, Gabriela Barreiro, Antonia F Stepan, Peter Cornelius

Chem Res Toxicol· December 2011

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Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor.
Vincent Mascitti, Benjamin D Stevens, Chulho Choi, Kim F McClure, Cristiano R W Guimarães, Peter Cornelius

Bioorg Med Chem Lett· March 2011

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Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist response.
Kim F McClure, Etzer Darout, Cristiano R W Guimarães, Michael P DeNinno, Vincent Mascitti, Peter Cornelius

J Med Chem· March 2011

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Intrinsic electrophilicity of a 4-substituted-5-cyano-6-(2-methylpyridin-3-yloxy)pyrimidine derivative: structural characterization of glutathione conjugates in vitro.
Amit S Kalgutkar, Vincent Mascitti, Raman Sharma, Gregory W Walker, Tim Ryder, Peter Cornelius

Chem Res Toxicol· February 2011

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Orally active and brain permeable proline amides as highly selective 5HT2c agonists for the treatment of obesity.
Kevin K-C Liu, Bruce A Lefker, Mark A Dombroski, Phoebe Chiang, Peter Cornelius

Bioorg Med Chem Lett· April 2010

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Design and synthesis of orally-active and selective azaindane 5HT2c agonist for the treatment of obesity.
Kevin K-C Liu, Peter Cornelius, Terrell A Patterson, Yuan Zeng, Stephanie Santucci

Bioorg Med Chem Lett· January 2010

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Design, synthesis, and pharmacology of fluorescently labeled analogs of serotonin: application to screening of the 5-HT2C receptor.
Peter Cornelius, Eunsun Lee, Wen Lin, Ruduan Wang, Wendy Werner

J Biomol Screen· April 2009

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Primary and secondary procedures in functional and aesthetic reconstruction of noma-associated complex central facial defects.
Goetz A Giessler, C Peter Cornelius, Sinikka Suominen, André Borsche, Alexander J Fieger

Plast Reconstr Surg· July 2007

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Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics.
Robert L Dow, Steven R Schneider, Ernest S Paight, Richard F Hank, Phoebe Chiang, Peter Cornelius

Bioorg Med Chem Lett· February 2003

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The regulation and activation of ciliary neurotrophic factor signaling proteins in adipocytes.
Sanjin Zvonic, Peter Cornelius, William C Stewart, Randall L Mynatt, Jacqueline M Stephens

J Biol Chem· January 2003

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