Publications by authors named "Robert G Roth"

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Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15-GFRaL-RET Complex Cell Signaling.
Anaïs F M Noisier, Jenny Sandmark, Fredrik Edfeldt, Anna Backmark, Johan Broddefalk, Robert G Roth

J Med Chem· October 2025

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Protein Expression via Transient Transfection of Mammalian Cells in a WAVE Bioreactor.
Jenny Gunnarsson, David I Fisher, Robert G Roth

Methods Mol Biol· June 2024

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Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.
Magdalena Malm, Chih-Chung Kuo, Mona Moradi Barzadd, Aman Mebrahtu, Num Wistbacka, Robert G Roth

Metab Eng· July 2022

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Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay.
Sophia Hober, Cecilia Hellström, Jennie Olofsson, Eni Andersson, Sofia Bergström, Robert G Roth, Ylva Lindroth

Clin Transl Immunology· July 2021

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Systematic Evaluation of CRISPRa and CRISPRi Modalities Enables Development of a Multiplexed, Orthogonal Gene Activation and Repression System.
Andrea Martella, Mike Firth, Benjamin J M Taylor, Anne Göppert, Emanuela M Cuomo, Robert G Roth

ACS Synth Biol· September 2019

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A protein chimera strategy supports production of a model "difficult-to-express" recombinant target.
Hirra Hussain, David I Fisher, Robert G Roth, W Mark Abbott, Manuel Alejandro Carballo-Amador

FEBS Lett· July 2018

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Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A Type X (sPLA-X) Inhibitors.
Laurent Knerr, Fabrizio Giordanetto, Peter Nordberg, Daniel Pettersen, Nidhal Selmi, Robert G Roth

ACS Med Chem Lett· July 2018

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Design of Selective sPLA-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1-indol-1-yl]pyridine-2-yl}propanoic Acid.
Fabrizio Giordanetto, Laurent Knerr, Peter Nordberg, Daniel Pettersen, Nidhal Selmi, Robert G Roth

ACS Med Chem Lett· July 2018

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Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.
Jenny Sandmark, Göran Dahl, Linda Öster, Bingze Xu, Patrik Johansson, Robert G Roth

J Biol Chem· April 2018

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Use of a protein engineering strategy to overcome limitations in the production of "Difficult to Express" recombinant proteins.
Hirra Hussain, David I Fisher, W Mark Abbott, Robert G Roth, Alan J Dickson

Biotechnol Bioeng· October 2017

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MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes.
Mathijs Baens, Luca Bonsignore, Riet Somers, Charlotte Vanderheydt, Stephen D Weeks, Robert G Roth

PLoS One· April 2015

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