Publications by authors named "Robert Sims"

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E
Effect of immunosuppression on hESC-derived retina organoids in vitro and in vivo.
Robert Sims, Bin Lin, Yuntian Xue, Raghda Fouda, Bryce T McLelland

Stem Cell Res Ther· April 2025

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Patient Questions Surrounding Posterior Nasal Nerve Ablation for Chronic Rhinitis.
Daniel Gorelik, Samuel E Razmi, Robert Kenneth Sims, Aatin K Dhanda, Masayoshi Takashima

OTO Open· June 2024

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Lysine Methyltransferase SMYD1 Regulates Myogenesis via skNAC Methylation.
Li Zhu, Mark A Brown, Robert J Sims, Gayatri R Tiwari, Hui Nie

Cells· June 2023

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.
Alexander M Taylor, Chris Bailey, Lisa D Belmont, Robert Campbell, Nico Cantone, Robert J Sims

J Med Chem· August 2022

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A requirement for astrocyte IPR2 signaling for whisker experience-dependent depression and homeostatic upregulation in the mouse barrel cortex.
John B Butcher, Robert E Sims, Neville M Ngum, Amjad H Bazzari, Stuart I Jenkins

Front Cell Neurosci· August 2022

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Colitis Cystica Profunda: A Rare Mimicker of Colorectal Neoplasia.
Timothy A Zaki, Mireille Mbah, Mariam Mir, Robert D Sims, Amin Amin

Dig Dis Sci· July 2022

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CREBBP/EP300 acetyltransferase inhibition disrupts FOXA1-bound enhancers to inhibit the proliferation of ER+ breast cancer cells.
Archana Bommi-Reddy, Sungmi Park-Chouinard, David N Mayhew, Esteban Terzo, Aparna Hingway, Robert J Sims

PLoS One· April 2022

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Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity.
Jacob I Stuckey, Nico R Cantone, Alexandre Côté, Shilpi Arora, Valerie Vivat, Robert J Sims

J Biol Chem· August 2021

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Correction to: Applications of 3D printing in breast cancer management.
Arpine Galstyan, Michael J Bunker, Fluvio Lobo, Robert Sims, James Inziello

3D Print Med· July 2021

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Applications of 3D printing in breast cancer management.
Arpine Galstyan, Michael J Bunker, Fluvio Lobo, Robert Sims, James Inziello

3D Print Med· February 2021

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Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors.
Annissa J Huhn, Anna S Gardberg, Florence Poy, Francois Brucelle, Valerie Vivat, Robert Sims

ChemMedChem· June 2020

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Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time.
Avinash Khanna, Alexandre Côté, Shilpi Arora, Ludivine Moine, Victor S Gehling, Robert J Sims

ACS Med Chem Lett· June 2020

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Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor.
Jonathan E Wilson, Gaurav Patel, Chirag Patel, Francois Brucelle, Annissa Huhn, Robert J Sims

ACS Med Chem Lett· June 2020

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Bromodomains: a new target class for drug development.
Andrea G Cochran, Andrew R Conery, Robert J Sims

Nat Rev Drug Discov· August 2019

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Supine magnetic resonance defecography for evaluation of anterior compartment prolapse: Comparison with upright voiding cystourethrogram.
Neil M Kumar, Gaurav Khatri, Alana L Christie, Robert Sims, Ivan Pedrosa

Eur J Radiol· August 2019

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Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC.
Brett A Johnson, Margaret Coutts, Hillary M Vo, Xinya Hao, Nida Fatima, Robert J Sims

Fluids Barriers CNS· August 2018

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Astrocyte-Mediated Neuronal Synchronization Properties Revealed by False Gliotransmitter Release.
Tiina M Pirttimaki, Robert E Sims, Gregory Saunders, Serena A Antonio, Neela Krushna Codadu

J Neurosci· October 2017

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The Influence of a KDT501, a Novel Isohumulone, on Adipocyte Function in Humans.
Brian S Finlin, Beibei Zhu, Bernard P Kok, Cristina Godio, Philip M Westgate, Robert Sims

Front Endocrinol (Lausanne)· September 2017

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GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2).
Terry D Crawford, James E Audia, Steve Bellon, Daniel J Burdick, Archana Bommi-Reddy, Robert J Sims

ACS Med Chem Lett· July 2017

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Effects of KDT501 on Metabolic Parameters in Insulin-Resistant Prediabetic Humans.
Philip A Kern, Brian S Finlin, Dorothy Ross, Tania Boyechko, Beibei Zhu, Robert Sims

J Endocr Soc· June 2017

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Regulation of GLI Underlies a Role for BET Bromodomains in Pancreatic Cancer Growth and the Tumor Microenvironment.
Yinshi Huang, Sabikun Nahar, Akifumi Nakagawa, Maite G Fernandez-Barrena, Jennifer A Mertz, Robert J Sims

Clin Cancer Res· August 2016

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Correction: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma.
Andrew R Conery, Richard C Centore, Adrianne Neiss, Patricia J Keller, Shivangi Joshi, Robert J Sims

Elife· July 2016

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Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition.
Srimoyee Ghosh, Alexander Taylor, Melissa Chin, Hon-Ren Huang, Andrew R Conery, Robert J Sims

J Biol Chem· June 2016

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Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637).
Alexander M Taylor, Alexandre Côté, Michael C Hewitt, Richard Pastor, Yves Leblanc, Robert J Sims

ACS Med Chem Lett· May 2016

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Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains.
Alexander M Taylor, Rishi G Vaswani, Victor S Gehling, Michael C Hewitt, Yves Leblanc, Robert J Sims

ACS Med Chem Lett· February 2016

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