Publications by authors named "Rodolfo Gasser"

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Selective and brain-penetrant HCN1 inhibitors reveal links between synaptic integration, cortical function, and working memory.
Eva Harde, Markus Hierl, Michael Weber, David Waiz, Roger Wyler, Rodolfo Gasser

Cell Chem Biol· March 2024

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Synthesis, Characterization, and Evaluation of a Novel Potent Autotaxin-Inhibitor.
Daniel Hunziker, Sabrina Reinehr, Marina Palmhof, Natalie Wagner, Thomas Biniasch, Rodolfo Gasser

Front Pharmacol· January 2022

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Basmisanil, a highly selective GABA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man.
Joerg F Hipp, Frederic Knoflach, Robert Comley, Theresa M Ballard, Michael Honer, Rodolfo Gasser

Sci Rep· April 2021

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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome.
Hans Richter, Alexander L Satz, Marc Bedoucha, Bernd Buettelmann, Ann C Petersen, Rodolfo Gasser

ACS Chem Biol· January 2019

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Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime.
Solange Moll, Yukari Yasui, Ahmed Abed, Takeshi Murata, Hideaki Shimada, Rodolfo Gasser

J Transl Med· June 2018

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The PA Endonuclease Inhibitor RO-7 Protects Mice from Lethal Challenge with Influenza A or B Viruses.
Jeremy C Jones, Bindumadhav M Marathe, Peter Vogel, Rodolfo Gasser, Isabel Najera

Antimicrob Agents Chemother· May 2017

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Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.
Holger Kühne, Ulrike Obst-Sander, Bernd Kuhn, Aurelia Conte, Simona M Ceccarelli, Rodolfo Gasser

Bioorg Med Chem Lett· October 2016

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A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity In Vitro.
Jeremy C Jones, Bindumadhav M Marathe, Christian Lerner, Lukas Kreis, Rodolfo Gasser

Antimicrob Agents Chemother· September 2016

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Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome.
Carmen Martínez-Cué, Paula Martínez, Noemí Rueda, Rebeca Vidal, Susana García, Rodolfo Gasser

J Neurosci· February 2013

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Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABAA alpha5 inverse agonists with potential for the treatment of cognitive dysfunction.
Bernd Buettelmann, Theresa M Ballard, Rodolfo Gasser, Holger Fischer, Maria-Clemencia Hernandez

Bioorg Med Chem Lett· October 2009

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The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA alpha5 inverse agonists for the treatment of cognitive dysfunction.
Henner Knust, Guido Achermann, Theresa Ballard, Bernd Buettelmann, Rodolfo Gasser

Bioorg Med Chem Lett· October 2009

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RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors.
Theresa M Ballard, Frédéric Knoflach, Eric Prinssen, Edilio Borroni, Jeffrey A Vivian, Rodolfo Gasser

Psychopharmacology (Berl)· January 2009

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Mechanisms of benzarone and benzbromarone-induced hepatic toxicity.
Priska Kaufmann, Michael Török, Anya Hänni, Paul Roberts, Rodolfo Gasser

Hepatology· April 2005

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Discriminating different classes of toxicants by transcript profiling.
Guido Steiner, Laura Suter, Franziska Boess, Rodolfo Gasser, Maria Cristina de Vera

Environ Health Perspect· August 2004

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Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems.
Franziska Boess, Markus Kamber, Simona Romer, Rodolfo Gasser, Dieter Muller

Toxicol Sci· June 2003

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Use of gene chip technology for the characterisation of the regulation of renal transport processes and of nephrotoxicity in rats.
Christian Fleck, Laura Sutter, Dorothea Appenroth, Berit Koch, Tobias Meinhold, Rodolfo Gasser

Exp Toxicol Pathol· June 2003

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Pharmacogenetic analysis of adverse drug effect reveals genetic variant for susceptibility to liver toxicity.
Gonzalo Acuña, Dorothee Foernzler, Diane Leong, Michael Rabbia, Ralf Smit, Rodolfo Gasser

Pharmacogenomics J· May 2003

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Modulation of gene and protein expression by carbon tetrachloride in the rat liver.
Michael Fountoulakis, Maria-Christina de Vera, Flavio Crameri, Franziska Boess, Rodolfo Gasser

Toxicol Appl Pharmacol· August 2002

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