Publications by authors named "Steven Higginbottom"

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Genome-scale resources in the infant gut symbiont Bifidobacterium breve reveal genetic determinants of colonization and host-microbe interactions.
Anthony L Shiver, Jiawei Sun, Rebecca Culver, Arvie Violette, Char Wynter, Steven Higginbottom

Cell· April 2025

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A gut pathobiont regulates circulating glycine and host metabolism in a twin study comparing vegan and omnivorous diets.
Matthew M Carter, Xianfeng Zeng, Catherine P Ward, Matthew Landry, Dalia Perelman, Steven Higginbottom

medRxiv· January 2025

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Improved mouse models of the small intestine microbiota using region-specific sampling from humans.
Rebecca N Culver, Sean Paul Spencer, Arvie Violette, Evelyn Giselle Lemus Silva, Tadashi Takeuchi, Steven K Higginbottom

bioRxiv· April 2024

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Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition.
Elias R Gerrick, Soumaya Zlitni, Patrick T West, Matthew M Carter, Claire M Mechler, Steven K Higginbottom

Cell· January 2024

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Hadza require diet-derived microbiota-accessible carbohydrates to persist in mice.
Rebecca H Gellman, Matthew R Olm, Nicolas Terrapon, Fatima Enam, Steven K Higginbottom

Cell Rep· November 2023

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Mapping the T cell repertoire to a complex gut bacterial community.
Kazuki Nagashima, Aishan Zhao, Katayoon Atabakhsh, Minwoo Bae, Jamie E Blum, Steven Higginbottom

Nature· September 2023

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A mutant fitness compendium in Bifidobacteria reveals molecular determinants of colonization and host-microbe interactions.
Anthony L Shiver, Jiawei Sun, Rebecca Culver, Arvie Violette, Charles Wynter, Steven Higginbottom

bioRxiv· August 2023

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Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome.
Min Wang, Lucas J Osborn, Sunit Jain, Xiandong Meng, Allison Weakley, Steven Higginbottom

Cell· June 2023

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Hadza Require Diet-derived Microbiota Accessible Carbohydrates to Persist in Mice.
Rebecca H Gellman, Matthew R Olm, Nicolas Terrapon, Fatima Enam, Steven K Higginbottom

bioRxiv· March 2023

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Butyrate Differentiates Permissiveness to Clostridioides difficile Infection and Influences Growth of Diverse C. difficile Isolates.
Daniel A Pensinger, Andrea T Fisher, Horia A Dobrila, William Van Treuren, Jackson O Gardner, Steven K Higginbottom

Infect Immun· February 2023

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Host-microbe co-metabolism via MCAD generates circulating metabolites including hippuric acid.
Kali M Pruss, Haoqing Chen, Yuanyuan Liu, William Van Treuren, Steven K Higginbottom

Nat Commun· January 2023

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Design, construction, and in vivo augmentation of a complex gut microbiome.
Alice G Cheng, Po-Yi Ho, Andrés Aranda-Díaz, Sunit Jain, Feiqiao B Yu, Steven Higginbottom

Cell· September 2022

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Clostridium sporogenes uses reductive Stickland metabolism in the gut to generate ATP and produce circulating metabolites.
Yuanyuan Liu, Haoqing Chen, William Van Treuren, Bi-Huei Hou, Steven K Higginbottom

Nat Microbiol· May 2022

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Establishment and characterization of stable, diverse, fecal-derived in vitro microbial communities that model the intestinal microbiota.
Andrés Aranda-Díaz, Katharine Michelle Ng, Tani Thomsen, Imperio Real-Ramírez, Dylan Dahan, Steven K Higginbottom

Cell Host Microbe· February 2022

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Oxidative ornithine metabolism supports non-inflammatory C. difficile colonization.
Kali M Pruss, Fatima Enam, Eric Battaglioli, Mary DeFeo, Oscar R Diaz, Steven K Higginbottom

Nat Metab· January 2022

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Quantifying rapid bacterial evolution and transmission within the mouse intestine.
Kimberly S Vasquez, Lisa Willis, Nate J Cira, Katharine M Ng, Miguel F Pedro, Steven K Higginbottom

Cell Host Microbe· September 2021

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A metabolomics pipeline for the mechanistic interrogation of the gut microbiome.
Shuo Han, Will Van Treuren, Curt R Fischer, Bryan D Merrill, Brian C DeFelice, Steven K Higginbottom

Nature· July 2021

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Recovery of the Gut Microbiota after Antibiotics Depends on Host Diet, Community Context, and Environmental Reservoirs.
Katharine Michelle Ng, Andrés Aranda-Díaz, Carolina Tropini, Matthew Ryan Frankel, William Van Treuren, Steven Kyle Higginbottom

Cell Host Microbe· October 2020

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A metabolic pathway for bile acid dehydroxylation by the gut microbiome.
Masanori Funabashi, Tyler L Grove, Min Wang, Yug Varma, Molly E McFadden, Steven Higginbottom

Nature· June 2020

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A Metabolic Pathway for Activation of Dietary Glucosinolates by a Human Gut Symbiont.
Catherine S Liou, Shannon J Sirk, Camil A C Diaz, Andrew P Klein, Curt R Fischer, Steven K Higginbottom

Cell· February 2020

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Depletion of microbiome-derived molecules in the host using genetics.
Chun-Jun Guo, Breanna M Allen, Kamir J Hiam, Dylan Dodd, Will Van Treuren, Steven Higginbottom

Science· December 2019

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Western diet regulates immune status and the response to LPS-driven sepsis independent of diet-associated microbiome.
Brooke A Napier, Marta Andres-Terre, Liliana M Massis, Andrew J Hryckowian, Steven K Higginbottom

Proc Natl Acad Sci U S A· February 2019

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Genetic Variation of the SusC/SusD Homologs from a Polysaccharide Utilization Locus Underlies Divergent Fructan Specificities and Functional Adaptation in Strains.
Payal Joglekar, Erica D Sonnenburg, Steven K Higginbottom, Kristen A Earle, Carl Morland

mSphere· October 2018

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Transient Osmotic Perturbation Causes Long-Term Alteration to the Gut Microbiota.
Carolina Tropini, Eli Lin Moss, Bryan Douglas Merrill, Katharine Michelle Ng, Steven Kyle Higginbottom

Cell· June 2018

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