Publications by authors named "Caroline Lewis"

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Distinct S-adenosylmethionine synthases link phosphatidylcholine to mitochondrial function and stress survival.
Athena L Munden, Arjamand Mushtaq, Dominique S Lui, Katherine M Edwards, Daniel P Higgins, Caroline A Lewis

PLoS Biol· December 2025

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HSD17B13 Couples Hepatocyte Lipid Metabolism to Stellate Cell Activation via TGFb-1 Signaling.
Naideline Raymond, Lawrence Lifshitz, Kyounghee Min, Caroline A Lewis, Giorgis Isaac

bioRxiv· October 2025

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Atlas of Lysosomal Aging Reveals a Molecular Clock of Storage Disorder-Associated Metabolites.
Anna M Puszynska, Thao P Nguyen, Andrew L Cangelosi, Andrea Armani, Justin M Roberts, Caroline A Lewis

bioRxiv· September 2025

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Rhodoquinone carries electrons in the mammalian electron transport chain.
Jonathan Valeros, Madison Jerome, Tenzin Tseyang, Paula Vo, Thang Do, Caroline A Lewis

Cell· February 2025

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Functional Specialization of S-Adenosylmethionine Synthases Links Phosphatidylcholine to Mitochondrial Function and Stress Survival.
Athena L Munden, Dominique S Lui, Daniel P Higgins, Matthew J Fanelli, Thien-Kim Ngyuen, Caroline Lewis

bioRxiv· February 2025

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A Microphysiological Model of Progressive Human Hepatic Insulin Resistance.
Dominick J Hellen, Jessica Ungerleider, Erin Tevonian, Pierre Sphabmixay, Priyatanu Roy, Caroline Lewis

bioRxiv· January 2025

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SLC25A38 is required for mitochondrial pyridoxal 5'-phosphate (PLP) accumulation.
Izabella A Pena, Jeffrey S Shi, Sarah M Chang, Jason Yang, Samuel Block, Caroline A Lewis

Nat Commun· January 2025

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Cancer tissue of origin constrains the growth and metabolism of metastases.
Sharanya Sivanand, Yetis Gultekin, Peter S Winter, Sidney Y Vermeulen, Konstantine M Tchourine, Caroline A Lewis

Nat Metab· September 2024

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Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability.
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Caroline A Lewis

Elife· May 2024

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A2-165 metabolizes host- and media-derived chemicals and induces transcriptional changes in colonic epithelium in GuMI human gut microphysiological system.
Yu-Ja Huang, Caroline A Lewis, Charles Wright, Kirsten Schneider, John Kemmitt

Microbiome Res Rep· May 2024

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Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability.
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Caroline A Lewis

bioRxiv· April 2024

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Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells.
Samantha J Linder, Tiziano Bernasocchi, Bárbara Martínez-Pastor, Kelly D Sullivan, Matthew D Galbraith, Caroline A Lewis

Nat Metab· December 2023

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Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
Keene L Abbott, Ahmed Ali, Dominick Casalena, Brian T Do, Raphael Ferreira, Caroline A Lewis

Cell Chem Biol· September 2023

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Inpatient Rehabilitation Issues Related to COVID-19.
Amanda A Kelly, Caroline A Lewis, Miguel X Escalon

Phys Med Rehabil Clin N Am· August 2023

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A nationwide serological survey for Dirofilaria immitis in companion cats in the United States of America: 3.5% antibody and 0.3% antigen positivity.
Daniel Felipe Barrantes Murillo, Lindsay Starkey, Theresa Wood, Rachel Smith, Byron Blagburn, Caroline Lewis

Parasit Vectors· August 2023

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S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress.
Adwait A Godbole, Sneha Gopalan, Thien-Kim Nguyen, Alexander L Munden, Dominique S Lui, Caroline A Lewis

Elife· February 2023

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Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
Keene L Abbott, Ahmed Ali, Dominick Casalena, Brian T Do, Raphael Ferreira, Caroline A Lewis

bioRxiv· February 2023

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Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading.
Nimansha Jain, Caroline A Lewis, Jason D Ulrich, David M Holtzman

J Exp Med· January 2023

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CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.
Nouf N Laqtom, Wentao Dong, Uche N Medoh, Andrew L Cangelosi, Vimisha Dharamdasani, Caroline A Lewis

Nature· September 2022

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Nucleotide imbalance decouples cell growth from cell proliferation.
Frances F Diehl, Teemu P Miettinen, Ryan Elbashir, Christopher S Nabel, Alicia M Darnell, Caroline A Lewis

Nat Cell Biol· August 2022

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Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization.
Michael R MacArthur, Sarah J Mitchell, Katia S Chadaideh, J Humberto Treviño-Villarreal, Jonathan Jung, Caroline A Lewis

Cell Rep· August 2022

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Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine.
Andrew L Cangelosi, Anna M Puszynska, Justin M Roberts, Andrea Armani, Thao P Nguyen, Caroline A Lewis

Science· July 2022

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Author Correction: Histidine catabolism is a major determinant of methotrexate sensitivity.
Naama Kanarek, Heather R Keys, Jason R Cantor, Caroline A Lewis, Sze Ham Chan

Nature· February 2022

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Fumarate is a terminal electron acceptor in the mammalian electron transport chain.
Jessica B Spinelli, Paul C Rosen, Hans-Georg Sprenger, Anna M Puszynska, Jessica L Mann, Caroline A Lewis

Science· December 2021

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