Publications by authors named "Jennifer Pierson"

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Use of new approach methodologies (NAMs) in epilepsy research and seizure risk assessment.
Ruth A Roberts, Mamta Behl, Helena T Hogberg, Eduardo Dunayevich, Michael Morton, Jennifer B Pierson

Drug Discov Today· December 2025

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Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development.
Jennifer Beck Pierson, Anthony Bahinski, Brian Berridge, Daniel Bramham, Todd Bourcier

Int J Toxicol· November 2025

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Evaluation of Biomarkers to Detect Early Prothrombotic Imbalance in Rat Models of Hypercoagulability Induced by Thromboplastin Infusion and Hypofibrinolysis Induced by Tranexamic Acid.
Marjory B Brooks, Cindy E Fishman, Mohanapriya Kamalakannan, Paula Katavolos, Claire E O'Brien, Jennifer B Pierson

Toxicol Pathol· October 2025

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Genetic mixing in conservation translocations increases diversity of a keystone threatened species, Bettongia lesueur.
Heidi M Nistelberger, Emily Roycroft, Anna J Macdonald, Shelley McArthur, Lauren C White, Jennifer Pierson

Mol Ecol· September 2025

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Multi-laboratory comparisons of manual patch clamp hERG data generated using standardized protocols and following ICH S7B Q&A 2.1 best practices.
Claudia Alvarez Baron, Jun Zhao, Huimei Yu, Ming Ren, Nicolas Thiebaud, Jennifer Beck Pierson

Sci Rep· August 2025

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An overview of drug-induced sodium channel blockade and changes in cardiac conduction: Implications for drug safety.
Khuram W Chaudhary, Colleen E Clancy, Pei-Chi Yang, Jennifer B Pierson, Alan L Goldin

Clin Transl Sci· December 2024

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Assessment of corrected JT-peak (JTpc) and Tpeak-to-Tend (TpTec) as proarrhythmia biomarkers in non-human primates: Outcome from a HESI consortium.
Emmanuel Boulay, Simon Authier, Theresa Bartko, Andrea Greiter-Wilke, Derek Leishman, Jennifer Pierson

J Pharmacol Toxicol Methods· September 2024

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Detection of contractility changes in the heart from arterial blood pressure data using symmetric Projection Attractor Reconstruction.
Esther Bonet-Luz, Manasi Nandi, Mark I Christie, Jennifer Doyle, Jennifer B Pierson

J Pharmacol Toxicol Methods· September 2024

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Development of a pharmaceutical database as an aid to the nonclinical detection of drug-induced cardiac toxicity.
Donald De Alwis, C Michael Foley, Eugene Herman, Adam P Hill, Peter K Hoffmann, Jennifer Pierson

J Pharmacol Toxicol Methods· June 2024

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Collaborative science in action: A 20 year perspective from the Health and Environmental Sciences Institute (HESI) Cardiac Safety Committee.
Jennifer B Pierson, Brian Berridge, Ksenia Blinova, Marjory B Brooks, Sandy Eldridge

J Pharmacol Toxicol Methods· June 2024

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Challenging the status quo: a framework for mechanistic and human-relevant cardiovascular safety screening.
Brian Berridge, Jennifer Pierson, Syril Pettit, Norman Stockbridge

Front Toxicol· March 2024

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Analyzing captive breeding outcomes to inform reintroduction practice: lessons from the pookila ().
Kiarrah J Smith, Maldwyn J Evans, Iain J Gordon, Jennifer C Pierson, Jenny Newport

J Mammal· October 2023

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The incidence of spontaneous arrhythmias in telemetered beagle dogs, Göttingen Minipigs and Cynomolgus non-human primates: A HESI consortium retrospective analysis.
Emmanuel Boulay, Loïs S Miraucourt, Michael K Pugsley, Matthew M Abernathy, Ray Chui, Jennifer B Pierson

J Pharmacol Toxicol Methods· May 2023

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Comprehensive Collection of Current Methods for Contractility and Electrophysiology Recordings in Human Cardiac Cells.
Ksenia Blinova, Jennifer Pierson, Akshay Narkar

J Vis Exp· March 2023

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Mini Safe Havens for population recovery and reintroductions 'beyond-the-fence'.
Kiarrah J Smith, Maldwyn J Evans, Iain J Gordon, Jennifer C Pierson, Simon Stratford

Biodivers Conserv· November 2022

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The Challenges of Predicting Drug-Induced QTc Prolongation in Humans.
Jean-Pierre Valentin, Peter Hoffmann, Catherine Ortemann-Renon, John Koerner, Jennifer Pierson

Toxicol Sci· April 2022

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Use of the ZDF rat to model dietary fat induced hypercoagulability is limited by progressive and fatal nephropathy.
Michael K Pugsley, Marjory B Brooks, Cindy E Fishman, Paula Katavolos, Alan Y Chiang, Jennifer B Pierson

J Pharmacol Toxicol Methods· November 2021

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Ongoing declines of woodland birds: Are restoration plantings making a difference?
Donna J Belder, Jennifer C Pierson, Ashwin C Rudder, David B Lindenmayer

Ecol Appl· April 2021

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Can We Panelize Seizure?
Ruth Roberts, Simon Authier, R Daniel Mellon, Michael Morton, Ikuro Suzuki, Jennifer B Pierson

Toxicol Sci· January 2021

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Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.
Gary Gintant, Emily Pfeiffer Kaushik, Tromondae Feaster, Sonja Stoelzle-Feix, Yasunari Kanda, Jennifer Beck Pierson

Regul Toxicol Pharmacol· November 2020

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Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation.
Eric I Rossman, Frank Cools, Jason Cordes, Deborah Dhuyvetter, Jennifer M Doyle, Jennifer B Pierson

J Pharmacol Toxicol Methods· September 2020

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Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
James Kramer, Herbert M Himmel, Anders Lindqvist, Sonja Stoelzle-Feix, Khuram W Chaudhary, Jennifer Beck Pierson

Sci Rep· July 2020

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Revegetation and reproduction: do restoration plantings in agricultural landscapes support breeding populations of woodland birds?
Donna J Belder, Jennifer C Pierson, Karen Ikin, David B Lindenmayer

Oecologia· April 2020

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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
James Kramer, Herbert M Himmel, Anders Lindqvist, Sonja Stoelzle-Feix, Khuram W Chaudhary, Jennifer Beck Pierson

Sci Rep· March 2020

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Considerations for an , Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes.
Alexandre J S Ribeiro, Brian D Guth, Michael Engwall, Sandy Eldridge, C Michael Foley, Jennifer B Pierson

Front Pharmacol· August 2019

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