Publications by authors named "Martyn Banks"

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Challenges and Opportunities in Enabling High-Throughput, Miniaturized High Content Screening.
Debra Nickischer, Lisa Elkin, Normand Cloutier, Jonathan O'Connell, Martyn Banks

Methods Mol Biol· June 2018

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Discovery of Selective Cannabinoid CB Receptor Agonists by High-Throughput Screening.
Lisa M Ogawa, Neil T Burford, Yu-Hsien Liao, Caitlin E Scott, Ashley M Hine, Martyn Banks

SLAS Discov· April 2018

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Synergistic inhibition of Aβ production by combinations of γ-secretase modulators.
Alan S Robertson, Lawrence G Iben, Cong Wei, Jere E Meredith, Dieter M Drexler, Martyn Banks

Eur J Pharmacol· October 2017

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Evidence for Classical Cholinergic Toxicity Associated with Selective Activation of M1 Muscarinic Receptors.
Andrew Alt, Annapurna Pendri, Robert L Bertekap, Guo Li, Yulia Benitex, Martyn Banks

J Pharmacol Exp Ther· February 2016

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Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor.
Neil T Burford, Kathryn E Livingston, Meritxell Canals, Molly R Ryan, Lauren M L Budenholzer, Martyn Banks

J Med Chem· May 2015

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Identification of selective agonists and positive allosteric modulators for µ- and δ-opioid receptors from a single high-throughput screen.
Neil T Burford, Tom Wehrman, Daniel Bassoni, Jonathan O'Connell, Martyn Banks

J Biomol Screen· October 2014

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Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists.
Yingjie Zhu, John Watson, Mengjie Chen, Ding Ren Shen, Melissa Yarde, Martyn Banks

J Biomol Screen· August 2014

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Identification of small molecules that selectively inhibit diacylglycerol lipase-α activity.
Kingsley K Appiah, Yuval Blat, Barbara J Robertson, Bradley C Pearce, Donna L Pedicord, Martyn N Banks

J Biomol Screen· April 2014

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Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor.
Neil T Burford, Mary J Clark, Tom S Wehrman, Samuel W Gerritz, Martyn Banks

Proc Natl Acad Sci U S A· June 2013

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Development of a high-throughput calcium flux assay for identification of all ligand types including positive, negative, and silent allosteric modulators for G protein-coupled receptors.
Devin J Noblin, Robert L Bertekap, Neil T Burford, Adam Hendricson, Litao Zhang, Martyn Banks

Assay Drug Dev Technol· October 2012

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A high-throughput screen for receptor protein tyrosine phosphatase-gamma selective inhibitors.
Kingsley K Appiah, Walter A Kostich, Samuel W Gerritz, Yanling Huang, Brian D Hamman, Martyn N Banks

J Biomol Screen· June 2011

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Impact of high-throughput screening in biomedical research.
Ricardo Macarron, Martyn N Banks, Dejan Bojanic, David J Burns, Dragan A Cirovic

Nat Rev Drug Discov· March 2011

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Extraction, identification, and functional characterization of a bioactive substance from automated compound-handling plastic tips.
John Watson, Emily B Greenough, John E Leet, Michael J Ford, Dieter M Drexler, Martyn Banks

J Biomol Screen· June 2009

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Best practices in compound management for preserving compound integrity and accurately providing samples for assays.
Sandra L Matson, Moneesh Chatterjee, David A Stock, John E Leet, Elizabeth A Dumas, Martyn N Banks

J Biomol Screen· June 2009

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Efficient and effective compound management to support lead optimization.
Chad W Johnson, Moneesh Chatterjee, Steve Kubala, David Helm, John Houston, Martyn Banks

J Biomol Screen· June 2009

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Multiplexing a high-throughput liability assay to leverage efficiencies.
John Herbst, Monique Anthony, Jeremy Stewart, David Connors, Taosheng Chen, Martyn Banks

Assay Drug Dev Technol· June 2009

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Case study: impact of technology investment on lead discovery at Bristol-Myers Squibb, 1998-2006.
John G Houston, Martyn N Banks, Alastair Binnie, Stephen Brenner, Jonathan O'Connell

Drug Discov Today· January 2008

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Use of cryopreserved transiently transfected cells in high-throughput pregnane X receptor transactivation assay.
Zhengrong Zhu, Jaime Puglisi, David Connors, Jeremy Stewart, John Herbst, Martyn Banks

J Biomol Screen· March 2007

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Analysis of cellular events using CellCard System in cell-based high-content multiplexed assays.
Taosheng Chen, George Hansen, Oren Beske, Kristin Yates, Yingjie Zhu, Martyn Banks

Expert Rev Mol Diagn· September 2005

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Coactivators in assay design for nuclear hormone receptor drug discovery.
Taosheng Chen, Wen Xie, Michele Agler, Martyn Banks

Assay Drug Dev Technol· December 2003

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An ultra-HTS process for the identification of small molecule modulators of orphan G-protein-coupled receptors.
Angela Cacace, Martyn Banks, Timothy Spicer, Francesca Civoli, John Watson

Drug Discov Today· September 2003

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