Publications by authors named "Tim S Wang"

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Targeting BRAF Class II and III Mutations in NSCLC with the pan-RAF inhibitor Exarafenib Reveals ARAF-KSR1-Mediated Resistance and Rational Combination Strategies.
Tadashi Manabe, Hannah C Bergo, Qingtian Li, Tim Sen Wang, Paul Severson

Res Sq· October 2025

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The Discovery of Exarafenib (KIN-2787): Overcoming the Challenges of Pan-RAF Kinase Inhibition.
Young K Chen, Toufike Kanouni, Lee D Arnold, Jason M Cox, Elisabeth Gardiner, Tim S Wang

J Med Chem· February 2024

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Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor.
Kevin Freeman-Cook, Robert L Hoffman, Nichol Miller, Jonathan Almaden, John Chionis, Tim S Wang

Cancer Cell· October 2021

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Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling.
Tim Sen Wang, Isabelle Coppens, Anna Saorin, Nathan Ryan Brady, Anne Hamacher-Brady

Dev Cell· June 2020

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KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect.
Kyle A Metz, Xinchen Teng, Isabelle Coppens, Heather M Lamb, Bart E Wagner, Tim Sen Wang

Ann Neurol· November 2018

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Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents.
Ram Naresh Pandey, Tim Sen Wang, Emmanuel Tadjuidje, Matthew G McDonald, Allan E Rettie

PLoS One· July 2014

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The EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromarone.
Emmanuel Tadjuidje, Tim Sen Wang, Ram Naresh Pandey, Saulius Sumanas, Richard A Lang

PLoS One· August 2012

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Multinodular lesions of the earlobes.
Thy Thy Do, Robert Gielczyk, Tim S Wang, Stephen Olsen, Lori Lowe

Arch Dermatol· April 2008

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