Publications by authors named "Tracy Staton"

Claim this Profile
A
Airway tryptase levels inform the lack of clinical efficacy of the tryptase inhibitor MTPS9579A in asthma.
Horace Rhee, Lindsay M Henderson, Rebecca N Bauer, Kit Wong, Tracy L Staton

Allergy· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A targeted amplicon next-generation sequencing assay for tryptase genotyping to support personalized therapy in mast cell-related disorders.
Olga Li, Jason A Hackney, David F Choy, Diana Chang, Rhea Nersesian, Tracy L Staton

PLoS One· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of the reproducibility of responses to nasal allergen challenge and effects of inhaled nasal corticosteroids.
Rebecca N Bauer, Yanqing Xie, Suzanne Beaudin, Lesley Wiltshire, Jennifer Wattie, Tracy Staton

Clin Exp Allergy· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A mechanistic PK/PD model to enable dose selection of the potent anti-tryptase antibody (MTPS9579A) in patients with moderate-to-severe asthma.
Sharon M Rymut, Lindsay M Henderson, Victor Poon, Tracy L Staton, Fang Cai

Clin Transl Sci· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Astegolimab or Efmarodocokin Alfa in Patients With Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial.
Michael Waters, James A McKinnell, Andre C Kalil, Greg S Martin, Timothy G Buchman, Tracy Staton

Crit Care Med· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Integrated systems modeling of severe asthma: Exploration of IL-33/ST2 antagonism.
Kapil Gadkar, Justin Feigelman, Siddharth Sukumaran, Manoj C Rodrigo, Tracy Staton

CPT Pharmacometrics Syst Pharmacol· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effects of inhaled JAK inhibitor GDC-4379 on exhaled nitric oxide and peripheral biomarkers of inflammation.
Hubert Chen, Rebecca Kunder, Yixuan Zou, Tracy Staton, Rui Zhu

Pulm Pharmacol Ther· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Population Pharmacokinetics and Exposure-Response Relationships of Astegolimab in Patients With Severe Asthma.
Naoki Kotani, Michael Dolton, Robin J Svensson, Jakob Ribbing, Lena E Friberg, Tracy Staton

J Clin Pharmacol· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk.
Diana Chang, Julie Hunkapiller, Tushar Bhangale, Jens Reeder, Kiran Mukhyala, Tracy L Staton

Sci Rep· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dose-dependent inactivation of airway tryptase with a novel dissociating anti-tryptase antibody (MTPS9579A) in healthy participants: A randomized trial.
Sharon M Rymut, Siddharth Sukumaran, Gizette Sperinde, Meire Bremer, Joshua Galanter, Tracy L Staton

Clin Transl Sci· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Population repeated time-to-event analysis of exacerbations in asthma patients: A novel approach for predicting asthma exacerbations based on biomarkers, spirometry, and diaries/questionnaires.
Robin J Svensson, Jakob Ribbing, Naoki Kotani, Michael Dolton, Shweta Vadhavkar, Tracy Staton

CPT Pharmacometrics Syst Pharmacol· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effect of intranasal corticosteroid treatment on allergen-induced changes in group 2 innate lymphoid cells in allergic rhinitis with mild asthma.
Yanqing Xie, Xiaotian Ju, Suzanne Beaudin, Lesley Wiltshire, John Paul Oliveria, Tracy Staton

Allergy· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial.
Steven G Kelsen, Ioana O Agache, Weily Soong, Elliot Israel, Geoffrey L Chupp, Tracy L Staton

J Allergy Clin Immunol· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of a specific immunoassay to selectively measure active tryptase in airway samples.
Gizette Sperinde, Meire Bremer, Henry R Maun, Amos Baruch, Robert A Lazarus, Tracy Staton

Bioanalysis· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton

Cell· January 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton

Cell· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Change in type-2 biomarkers and related cytokines with prednisolone in uncontrolled severe oral corticosteroid dependent asthmatics: an interventional open-label study.
John Busby, Cecile T J Holweg, Akiko Chai, Peter Bradding, Fang Cai, Tracy Staton

Thorax· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IL-17A is associated with the breakdown of the blood-brain barrier in relapsing-remitting multiple sclerosis.
A Francesca Setiadi, Alexander R Abbas, Surinder Jeet, Kit Wong, Antje Bischof, Tracy Staton

J Neuroimmunol· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers.
Tracy L Staton, Kun Peng, Ryan Owen, David F Choy, Christopher R Cabanski

BMC Pulm Med· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Measurement of IL-17AA and IL-17FF as Pharmacodynamic Biomarkers to Demonstrate Target Engagement in the Phase I Study of MCAF5352A.
Kun Peng, Yehong Wang, Ketevan Siradze, Rich Erickson, Saloumeh K Fischer, Tracy L Staton

AAPS J· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Seasonal variability of severe asthma exacerbations and clinical benefit from lebrikizumab.
Tracy L Staton, Joseph R Arron, Julie Olsson, Cécile T J Holweg, John G Matthews

J Allergy Clin Immunol· May 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of a multi-matrix LC-MS/MS method for urea quantitation and its application in human respiratory disease studies.
Jianshuang Wang, Yang Gao, Drew W Dorshorst, Fang Cai, Meire Bremer, Tracy L Staton

J Pharm Biomed Anal· January 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biomarkers in the clinical development of asthma therapies.
Tracy L Staton, David F Choy, Joseph R Arron

Biomark Med· October 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.
Yonglian Sun, Ivan Peng, Joshua D Webster, Eric Suto, Justin Lesch, Tracy Staton

Sci Signal· December 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice.
Joerg Ermann, Tracy Staton, Jonathan N Glickman, Rene de Waal Malefyt, Laurie H Glimcher

Proc Natl Acad Sci U S A· June 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis