345,635 results match your criteria: "Alkylation"

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Increased DNA methylation of Igf2 in the male hippocampus regulates age-related deficits in synaptic plasticity and memory.
Shannon Kincaid, Courtney P Stickling, Kayla Farrell, Yeeun Bae, Morgan B Patrick

Brain Res Bull· October 2025

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Exercise as a geroprotector: focusing on epigenetic aging.
Takuji Kawamura, Mitsuru Higuchi, Zsolt Radak, Yasuyuki Taki

Aging (Albany NY)· July 2025

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Methylation clocks for evaluation of anti-aging interventions.
Josh Mitteldorf

Aging (Albany NY)· May 2025

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Investigating telomere length in progeroid syndromes: implications for aging disorders.
Luma Srour, Abeer Qannan, Junko Oshima, Andre Megarbane, Yosra Bejaoui

Aging (Albany NY)· May 2025

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Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial.
Heike A Bischoff-Ferrari, Stephanie Gängler, Maud Wieczorek, Daniel W Belsky, Joanne Ryan

March 2025

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EpiAge: a next-generation sequencing-based epigenetic clock for biological age assessment in saliva and blood across health and disease.
David Cheishvili, Sonia Do Carmo, Filippo Caraci, Margherita Grasso, A Claudio Cuello

Aging (Albany NY)· January 2025

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TERT activation targets DNA methylation and multiple aging hallmarks.
Hong Seok Shim, Jonathan Iaconelli, Xiaoying Shang, Jiexi Li, Zheng D Lan

Cell· July 2024

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Cigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis.
Chiara Herzog, Allison Jones, Iona Evans, Janhavi R Raut, Michal Zikan

Cancer Res· June 2024

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Epigenetic Genome Modifications during Pregnancy: The Impact of Essential Nutritional Supplements on DNA Methylation.
Maciej W Socha, Wojciech Flis, Mateusz Wartęga

February 2024

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Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease.
Xiaoyue Mei, Joshua Blanchard, Connor Luellen, Michael J Conboy, Irina M Conboy

Aging (Albany NY)· September 2023

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Chemically induced reprogramming to reverse cellular aging.
Jae-Hyun Yang, Christopher A Petty, Thomas Dixon-McDougall, Maria Vina Lopez, Alexander Tyshkovskiy

July 2023

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Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis.
Ledio Bocova, Wouter Hubens, Cordula Engel, Steffen Koschmieder, Edgar Jost

Clin Epigenetics· June 2023

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Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial.
R Waziry, C P Ryan, D L Corcoran, K M Huffman, M S Kobor

Nat Aging· March 2023

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Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series.
Kara N Fitzgerald, Tish Campbell, Suzanne Makarem, Romilly Hodges

Aging (Albany NY)· March 2023

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Roles of the Oxytocin Receptor (OXTR) in Human Diseases.
Karolina Pierzynowska, Lidia Gaffke, Magdalena Żabińska, Zuzanna Cyske, Estera Rintz

Int J Mol Sci· February 2023

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Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity.
Pedro S Marra, Takehiko Yamanashi, Kaitlyn J Crutchley, Nadia E Wahba, Zoe-Ella M Anderson

Aging (Albany NY)· February 2023

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Loss of epigenetic information as a cause of mammalian aging.
Jae-Hyun Yang, Motoshi Hayano, Patrick T Griffin, João A Amorim, Michael S Bonkowski

January 2023

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Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test.
Oleksandr Demidenko, Diogo Barardo, Valery Budovskii, Robb Finnemore, Francis R Palmer

November 2021

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Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set.
E A Klein, D Richards, A Cohn, M Tummala, R Lapham

Ann Oncol· September 2021

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Cellular reprogramming and epigenetic rejuvenation.
Daniel J Simpson, Nelly N Olova, Tamir Chandra

September 2021

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Alcohol and Cancer: Epidemiology and Biological Mechanisms.
Harriet Rumgay, Neil Murphy, Pietro Ferrari, Isabelle Soerjomataram

Nutrients· September 2021

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Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial.
Kara N Fitzgerald, Romilly Hodges, Douglas Hanes, Emily Stack, David Cheishvili

Aging (Albany NY)· April 2021

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Adipocyte epigenetic alterations and potential therapeutic targets in transgenerationally inherited lean and obese phenotypes following ancestral exposures.
Stephanie E King, Eric Nilsson, Daniel Beck, Michael K Skinner

December 2019

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Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review.
K González-Becerra, O Ramos-Lopez, E Barrón-Cabrera, J I Riezu-Boj, F I Milagro

October 2019

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Nutritional modulation of the epigenome and its implication for future health.
Mark A Burton, Karen A Lillycrop

Proc Nutr Soc· August 2019

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DNA methylation GrimAge strongly predicts lifespan and healthspan.
Ake T Lu, Austin Quach, James G Wilson, Alex P Reiner, Abraham Aviv

Aging (Albany NY)· January 2019

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RNA from Trained Can Induce an Epigenetic Engram for Long-Term Sensitization in Untrained .
Alexis Bédécarrats, Shanping Chen, Kaycey Pearce, Diancai Cai, David L Glanzman

eNeuro· January 2019

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Difference in cell death response between mitomycin C and 5-fluorouracil treatment studied using quartz crystal microbalance combined with simultaneous monitoring of viable cells.
Hao Long, Tomoyasu Sugiyama, Hiroshi Muramatsu

J Biol Phys· December 2025

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Exploratory analysis of gene aberrations and chemotherapy response: findings from a real-world database in Japan.
Naoya Ishibashi, Takashi Kamatani, Satoru Aoyama, Masanori Tokunaga, Yusuke Kinugasa

Br J Cancer· December 2025

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Short-term follow-up of anti-MAG neuropathy patients given bendamustine plus rituximab combination therapy.
N Bezou, P Morel, B Hivert, E Diab, P Merle

Rev Neurol (Paris)· December 2025

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Inhibition of NAMPT targets DNA damage response to sensitize alkylating chemotherapy in TP53 mutant mantle cell lymphoma.
Na Li, Yicen Liu, Linna Zhang, Saisai Guo, Zhihao Wu

Blood Adv· December 2025

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A cell type enrichment analysis tool for brain DNA methylation data (CEAM).
Joshua Müller, Valentin T Laroche, Jennifer Imm, Luke Weymouth, Joshua Harvey

Epigenetics· December 2026

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Ferric nitrate-mediated synthesis of functionalized 1,2,3-benzotriazinones from 2-aminobenzamides and 2-nitrobenzamides nitrate reduction strategy.
Sachu Kuriakose, Sruthi S Nair, Jeyakumar Kandasamy

Org Biomol Chem· December 2025

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A phase 1 study of orally administered 5-fluoro-2'-deoxycytidine with tetrahydrouridine in patients with refractory solid tumors.
Alice P Chen, Shivaani Kummar, Larry Rubinstein, Jennifer Zlott, Geraldine O'Sullivan Coyne

Cancer Chemother Pharmacol· December 2025

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Protein arginine methyltransferase 7-mediated arginine mono-methylation stabilizes SRY-box transcription factor 9 to promote non-small cell lung cancer progression.
Lin Zhang, Jingyi Xiang, Yali Feng, Gufang Shen, Xu Huang

Mol Biomed· December 2025

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Alkylation-based optimization of antifungal FPPS inhibitors yields a potent, broad-spectrum lipophilic zoledronate derivative.
Aidan Kane, Felcia Lai, Joanna G Rothwell, Thanh Thi Hue Dinh, Leona Campbell

mBio· December 2025

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Nickel-catalyzed reductive coupling of secondary alkyl bromides with alkynes to construct allylic difluoromethyl alkenes.
Jinxu Dong, Xiaohong Wen, Yihang Xu, Jiaming Chen, Yanli Yuan

Chem Commun (Camb)· December 2025

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Design, Synthesis, and Evaluation of β‑Lactamase Inhibitors as Potential Therapeutics for Antimicrobial Resistance.
Sania Batool, Rabia Farid, Syed Sikander Azam, Abbas Hassan

ACS Omega· December 2025

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Acetyl peroxy radical-initiated oxidation of oxygenated monoterpenes: functional group effects on reaction pathways.
Ida Karppinen, Dominika Pasik, Nanna Myllys

Environ Sci Atmos· December 2025

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Synthesis and anticancer potential of glycosides.
Shaukat Ali, Gul Rukh, Hanan A Ogaly, Rahaf Ajaj, Abdur Rauf

RSC Adv· December 2025

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Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation.
Guofang Shen, Timothy W Synold, Shanzay Khan, David A Horne, Christopher G Kanakry

Front Immunol· December 2025

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Epigenetic modifications in vascular inflammation.
Linyi Tang, Liyun Li, Yang Liu, Xin Zhang, Xinglin Wang

Front Immunol· December 2025

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Kendrick Mass Defect Filtering Enables High-Throughput Untargeted Annotation of Minor Phytocannabinoids: Toward Streamlined Phytocannabinomics.
Andrea Cerrato, Giuseppe Cannazza, Cinzia Citti, Aldo Laganà, Roberta Paris

ACS Meas Sci Au· December 2025

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Disrupting resistance: novel therapeutic approaches to combat multidrug resistance in fusion-negative rhabdomyosarcoma.
Silvia Codenotti, Francesco Marampon, Francesca Megiorni, Carlo Guglielmo Cattaneo, Stefano Gastaldello

Cancer Drug Resist· December 2025

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LPC-engineered liposomes activate transcytosis for paclitaxel brain delivery and potentiation of TTFields/TMZ via TALECT regimen in glioblastoma.
Qi Zhan, Kaikai Yi, Shixue Yang, Biao Hong, Dongyuan Su

Theranostics· December 2025

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High-resolution HIV-1 mA epitranscriptome reveals isoform-dependent methylation clusters and unique 2-LTR transcript modifications.
Delphine Naquin, Sandra Blanchet, Erwin van Dijk, Lisa Bertrand, Sylvie Grégoire

NAR Genom Bioinform· December 2025

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N-Heterocyclic carbene-ruthenium complexes synthesized by a hydrogen-bonding-assisted strategy for dehydrogenative rearrangement of esters.
Zhi-Yuan Gong, Sheng Tao, Xiao-Bin Li, Tao Wang, Fei Chen

Org Biomol Chem· December 2025

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A Riboflavin-Derived Flavinium Salt Mediates Chemoselective Methylation Reactions.
Tim Langschwager, Ekrem Suylu, Julian Zuber, Golo Storch

Chemistry· December 2025

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Unimolecular Micellization Strategy for Achieving NIR-II Excited Fluorophores with Enhanced Brightness in Aqueous Media.
Zelong Li, Na Li, Fan Wu, Jingkang Zheng, Gui-Long Wu

Angew Chem Int Ed Engl· December 2025

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Targeting KRAS G12D: Advances in Inhibitor Design.
Kaiyin Shi, Amin Li

Thorac Cancer· December 2025

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Late-stage adenine N6-alkylation of nucleos(t)ides and oligonucleotides via photoredox and copper co-catalytic decarboxylative C(sp3)-N coupling.
Ruoqian Xie, Guolan Xiao, Wanlu Li, Wenhao Luochen, Madiha Butt

Nat Commun· December 2025

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Optimization of bulkiness/dynamicity and pH utilizing N,N'-bis(5,6,7-trimethoxy-2-quinolylmethyl)-N,N'-dialkylethylenediamines as a Cd-specific fluorescent sensor.
Yuji Mikata, Saori Yasuda, Poonyawee Suwankeeree, Runo Ozaki, Hideo Konno

J Inorg Biochem· December 2025

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Direct γ-C(sp3)-H Acylation of Amide Derivatives via Cooperative NHC and Photoredox Catalysis.
Guihua Nie, Jun Sun, Qingqing Guo, Chengjiang Fang, Qianqian Guo

J Org Chem· December 2025

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Cold- and TRPM8-dependent shaking in mammals and birds.
Tudor Selescu, Ramona-Andreea Bivoleanu, Violeta-Maria Caragea, Mirela Iodi Carstens, Alexandra Manolache

Commun Biol· December 2025

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