1,757,361 results match your criteria: "Pharmacological and Toxicological Phenomena"

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Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension.
John M Flack, Michel Azizi, Jenifer M Brown, Jamie P Dwyer, Jakub Fronczek

October 2025

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Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis.
Sunhee Jung, Hosung Bae, Won-Suk Song, Yujin Chun, Johnny Le

Nat Metab· September 2025

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Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer.
Anna Martling, Ida Hed Myrberg, Mef Nilbert, Henrik Grönberg, Fredrik Granath

September 2025

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Therapeutic Targeting of Oncogene-Induced Transcription-Replication Conflicts in Pancreatic Ductal Adenocarcinoma.
Shanna J Smith, Fan Meng, Robert G Lingeman, Caroline M Li, Min Li

Gastroenterology· September 2025

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A systematic review and dose response meta analysis of Omega 3 supplementation on cognitive function.
Hossein Shahinfar, Zahra Yazdian, Neda Asgari Avini, Kimia Torabinasab, Sakineh Shab-Bidar

Sci Rep· August 2025

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Individual variations in glycemic responses to carbohydrates and underlying metabolic physiology.
Yue Wu, Ben Ehlert, Ahmed A Metwally, Dalia Perelman, Heyjun Park

July 2025

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Tirzepatide as Compared with Semaglutide for the Treatment of Obesity.
Louis J Aronne, Deborah Bade Horn, Carel W le Roux, Wayne Ho, Beverly L Falcon

N Engl J Med· July 2025

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An orally administered gene editing nanoparticle boosts chemo-immunotherapy in colorectal cancer.
Kai Zhao, Yu Yan, Xiao-Kang Jin, Ting Pan, Shi-Man Zhang

Nat Nanotechnol· July 2025

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Long-Term Exposure to Non-Steroidal Anti-Inflammatory Medication in Relation to Dementia Risk.
Ilse Vom Hofe, Bruno H Stricker, M Kamran Ikram, Frank J Wolters, M Arfan Ikram

J Am Geriatr Soc· May 2025

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Anti-HIV diterpenoids from Daphne pseudomezereum.
Kouharu Otsuki, Chihiro Hosoya, Riko Takamiya, Mayu Kimura, Takashi Kikuchi

Phytochemistry· April 2025

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Bioaccumulation of microplastics in decedent human brains.
Alexander J Nihart, Marcus A Garcia, Eliane El Hayek, Rui Liu, Marian Olewine

Nat Med· April 2025

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Atovaquone and selinexor as a novel combination treatment option in acute myeloid leukemia.
Stefanie Weiss, Bernhard Zdársky, Agnieszka Witalisz-Siepracka, Sophie Edtmayer, Anja Holzer

Cancer Lett· March 2025

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Tirzepatide for Obesity Treatment and Diabetes Prevention.
Ania M Jastreboff, Carel W le Roux, Adam Stefanski, Louis J Aronne, Bruno Halpern

N Engl J Med· March 2025

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Cannabidiol in Foods and Food Supplements: Evaluation of Health Risks and Health Claims.
Barbara E Engeli, Dirk W Lachenmeier, Patrick Diel, Sabine Guth, Maria A Villar Fernandez

Nutrients· January 2025

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Targeting resistant breast cancer stem cells in a three-dimensional culture model with oleuropein encapsulated in methacrylated alginate microparticles.
Ozlem Altundag-Erdogan, Rumeysa Tutar, Elif Yüce, Betül Çelebi-Saltik

December 2024

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Navigating the intricate in-vivo journey of lipid nanoparticles tailored for the targeted delivery of RNA therapeutics: a quality-by-design approach.
Elahe Haghighi, Samira Sadat Abolmaali, Ali Dehshahri, Seyed Ali Mousavi Shaegh, Negar Azarpira

J Nanobiotechnology· November 2024

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Cannabidiol Increases Psychotropic Effects and Plasma Concentrations of Δ-Tetrahydrocannabinol Without Improving Its Analgesic Properties.
Andriy A Gorbenko, Jules A A C Heuberger, Linda E Klumpers, Marieke L de Kam, Pamela K Strugala

Clin Pharmacol Ther· November 2024

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Time-Restricted Eating in Adults With Metabolic Syndrome : A Randomized Controlled Trial.
Emily N C Manoogian, Michael J Wilkinson, Monica O'Neal, Kyla Laing, Justina Nguyen

Ann Intern Med· November 2024

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Tolerance and efficient metabolization of extremely high ethanol concentrations by a social wasp.
Sofia Bouchebti, Yael Gershon, Alexander Gordin, Dorothée Huchon, Eran Levin

October 2024

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Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial.
Metha Yaikwawong, Laddawan Jansarikit, Siwanon Jirawatnotai, Somlak Chuengsamarn

October 2024

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The efficacy and safety of GLP-1 agonists in PCOS women living with obesity in promoting weight loss and hormonal regulation: A meta-analysis of randomized controlled trials.
Beatriz Austregésilo de Athayde De Hollanda Morais, Vitória Martins Prizão, Mariana de Moura de Souza, Beatriz Ximenes Mendes, Maria Luiza Rodrigues Defante

October 2024

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Low β-carotene bioaccessibility and bioavailability from high fat, dairy-based meal.
Johanita Kruger, Nadine Sus, Andrea Moser, Sophie Scholz, Guenther Adler

September 2024

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High-throughput virtual screening of phenylpyrimidine derivatives as selective JAK3 antagonists using computational methods.
Abdelmoujoud Faris, Ibrahim M Ibrahim, Hanine Hadni, Menana Elhallaoui

J Biomol Struct Dyn· September 2024

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Neurodegenerative disorders, metabolic icebergs, and mitohormesis.
Matthew C L Phillips, Martin Picard

Transl Neurodegener· September 2024

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Update on cannabis in human sexuality.
Denis Lissitsa, May Hovers, Michal Shamuilova, Tal Ezrapour, Leehe Peled-Avron

Psychopharmacology (Berl)· September 2024

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Revisiting resistant hypertension in kidney disease.
Shweta Bansal

Curr Opin Nephrol Hypertens· September 2024

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Optimal methods of vitamin D supplementation to prevent acute respiratory infections: a systematic review, dose-response and pairwise meta-analysis of randomized controlled trials.
Chih-Hung Wang, Lorenzo Porta, Ting-Kai Yang, Yu-Hsiang Wang, Tsung-Hung Wu

Nutr J· August 2024

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Beyond symbolic participation: youth-led organisations' voices and actions against antimicrobial resistance in Africa South of the Sahara.
Erick Venant Samwel, Roberta Biasiotto, Michael Mosha, Mirko Ancillotti

Glob Health Action· December 2025

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Ricinoleic Acid Potentiates Sodium Fluoride's Antibacterial Action Against Streptococcus mutans: A Synergistic Approach for Caries Control.
Ravichellam Sangavi, Nambiraman Malligarjunan, Shunmugiah Karutha Pandian, Shanmugaraj Gowrishankar

APMIS· December 2025

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Multi-Angle Bioactivity Cartography for Computational Screening and Mechanistic Analysis of AChE Inhibitors From Yellow Gastrodia elata.
Ruijun Sun, Yuchi Zhang, Jingying Xu, Ming Chen, Chunming Liu

Arch Pharm (Weinheim)· December 2025

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Phages Shape the Transformation of Organic Matter During Composting.
Yuanyuan Bao, Jan Dolfing, Ruirui Chen, Chongwen Qiu, Jianwei Zhang

Microb Biotechnol· December 2025

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YTHDF1 targets the chemotherapy response by suppressing NOTCH1-induced stemness in colorectal cancer.
Henley Cheung, Huarong Chen, Danyu Chen, Heming Zhou, Cong Liang

Signal Transduct Target Ther· December 2025

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Oral nutritional management in short bowel syndrome.
Astrid Verbiest, Lise De Meyere, Nelle Pauwels, Yasna Overloop, Tim Vanuytsel

Best Pract Res Clin Gastroenterol· December 2025

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Phase 1 study evaluating the safety, preliminary efficacy, and pharmacodynamics of recombinant interleukin-15 in combination with nivolumab and ipilimumab in patients with refractory cancers.
Jibran Ahmed, Geraldine O'Sullivan Coyne, Larry V Rubinstein, Sarah J Shin, Naoko Takebe

J Immunother Cancer· December 2025

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Etoposide activates CD8 T cell anti-tumor immunity in osteosarcoma through MHC I upregulation via tumor-secreted IL-33 mediated signaling.
Xin He, Hanjun Li, Haoyu Wang, Dongqing Zuo, Haoru Dong

J Immunother Cancer· December 2025

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Isolation of Four New Secondary Metabolites from the Cold Seep Chemosynthetic Ecosystem-Derived Fungus Arachnomyces bostrychodes.
Tokuya Teshima, Yusaku Sadahiro, Yuki Hitora, Yuriko Nagano, Sachiko Tsukamoto

Chem Pharm Bull (Tokyo)· December 2025

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Urinary Mineral Excretion in Healthy Saudi Infants and Toddlers.
Khalid A Alhasan, Walaa Alshammasi, Suha Salim, Abdulelah Alshauban, Ibrahim Sandokji

Nephrology (Carlton)· December 2025

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A First-in-Human, Single- and Multiple-Dose Study of APG777, a Half-Life-Extended Anti-IL-13 Monoclonal Antibody, in Healthy Volunteers.
Xiu Qin Lim, Erica Winter, Kristine Nograles, Jiahong Xu, Zhi-Qiang Zhang

Clin Transl Sci· December 2025

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High intestinal iron absorption induced by decreased hepcidin leads to imbalance of iron metabolism in aging mice.
Lili Qiu, Wei Xiong, Xiyu Qin, Jun Zhou, Yinhua Zhu

Biogerontology· December 2025

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When Should Clinical Mycology Laboratories Perform Antifungal Susceptibility Testing? Revisiting Practice Through the Lens of Intrinsic Resistance.
Cornelia Lass-Flörl, Sevtap Arikan-Akdagli

Mycopathologia· December 2025

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Genome-Wide DNA Methylation and RNA Analysis Reveal Epigenetic and Transcriptomic Changes in Carbapenem-Resistant Klebsiella pneumoniae Strains.
Jia Tao, Liru Wang, Lixin Yan, Xinxin Hu, Wei Hong

Curr Microbiol· December 2025

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Pharmacokinetics of a Single Oral Dose of Robenacoxib in Hispaniolan Parrots ().
Hailey B Penticoff, Thomas N Tully, Dharmikkumar Vora, Levent Dirikolu

J Avian Med Surg· December 2025

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The association of co-exposure to polycyclic aromatic hydrocarbons and phthalates with surrogate indicators of insulin resistance: a panel study.
Sha You, Lin Liu, Min Xiang, Lei Zhao, Wenting Guo

Environ Geochem Health· December 2025

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Unraveling the Anticancer Activity of Sunitinib Derivatives Through Modifications in Solvent-Exposed Regions: Synthesis, In Vitro Evaluation, and Computational Studies.
Robby Gus Mahardika, Ade Danova, Chanat Aonbangkhen, Jaruwan Chatwichien, Sutthida Wongsuwan

Arch Pharm (Weinheim)· December 2025

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Quinoline/Pyrido-Pyrimidine Derivatives as Tubulin Polymerization Inhibitors: Design, Synthesis, Computational, and Anticancer Evaluation.
Divyakshi Arya, Gulshan Aara Khan, Shweta Singh, Anjali Upadhyay, Bharat Prasad Sharma

Arch Pharm (Weinheim)· December 2025

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A Monitoring Method to Evaluate the Accumulation of Antimicrobial-Resistance Genes in Gram-Negative Bacteria Distributed in Environmental Water.
Nobuyoshi Yagi, Sora Miyazato, Nguyen Quoc Anh, Bui Thi Mai Huong, Itaru Hirai

Environ Microbiol Rep· December 2025

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Upregulation of lncRNA CASC2 alleviates neuroinflammation in acute ischemic stroke and exhibits protective effects by targeting miR-155 (CASC2 role in AIS).
Yuhao Zhang, Zhiyu Wang, Qingting Hu, Chenting Jin

Eur J Med Res· December 2025

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Vitamin C enhances cisplatin sensitivity in bladder cancer via 5hmC-mediated epigenetic modulation of ATF4.
Chunru Xu, Wenwei Ying, Yuhui He, Yucai Wu, Tai Tian

Clin Epigenetics· December 2025

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SEOH, a novel marine-derived spirostenoid: potent broad-spectrum antimicrobial activity against multidrug-resistant aquaculture pathogens.
Rewan Abdelaziz, Gamal El-Didamony, Azza S El-Demerdash, Rania A ElDaly

Appl Microbiol Biotechnol· December 2025

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HIV/AIDS compartmental model analysis with drug resistance treatment, vertical transmission, and optimal control theory.
Olumuyiwa James Peter, Shewafera Wondimagegnhu Teklu, Ghaniyyat Bolanle Balogun, Gbolahan Bolarin, Manalebish Debalike Asfaw

Sci Rep· December 2025

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High expression of formin-2 can promote ovarian cancer chemoresistance via immunosuppressive macrophages.
Shuo Feng, Yaping Wang, Ran Ren, Xiaotong Wang, Lu Han

Funct Integr Genomics· December 2025

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Enteric susceptibility profile: Finding hope amidst despair.
Ali Sufyan, Hameer Saif Talpur, Fiza Shafi, Shajee Siddiqui

J Pak Med Assoc· November 2025

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Association of Insulin Resistance and Insulin Secretion Indices and Glucose Metrics From Continuous Glucose Monitoring in People With Obesity.
Renata Belfort-DeAguiar, Catherine W Yeckel, Ahmed Elshafie, Ana Paula Comarella, Janice J Hwang

Diabetes Care· January 2026

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Dose-finding for dobutamine during transitional circulation in the very preterm infant: The study protocol.
Maria Sanchez-Holgado, Patricia Alvarez-Garcia, Maria Carmen Bravo, Fernando Cabañas, Manuela López Azorin

PLoS One· December 2025

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