Publications by authors named "BM Savall"

Claim this Profile
D
Discovery of Imidazo[1,2-]pyrazines and Pyrazolo[1,5-]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators.
Brad M Savall, Dongpei Wu, Devin M Swanson, Mark Seierstad, Nyantsz Wu

ACS Med Chem Lett· March 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.
Suchitra Ravula, Brad M Savall, Nyantsz Wu, Brian Lord, Kevin Coe

ACS Med Chem Lett· August 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
4
4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.
Michael A Letavic, Brad M Savall, Brett D Allison, Leah Aluisio, Jose Ignacio Andres

J Med Chem· June 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reply to "A Comment on 'Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8'".
Michael P Maher, Michael K Ameriks, Brad M Savall, Nicholas I Carruthers, Timothy W Lovenberg

J Pharmacol Exp Ther· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor.
Devin M Swanson, Brad M Savall, Kevin J Coe, Freddy Schoetens, Tatiana Koudriakova

J Med Chem· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The evolution of P2X7 antagonists with a focus on CNS indications.
Jason C Rech, Anindya Bhattacharya, Michael A Letavic, Brad M Savall

Bioorg Med Chem Lett· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8.
Michael P Maher, Nyantsz Wu, Suchitra Ravula, Michael K Ameriks, Brad M Savall

J Pharmacol Exp Ther· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical characterization of substituted 6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one P2X7 receptor antagonists.
Michael K Ameriks, Hong Ao, Nicholas I Carruthers, Brian Lord, Suchitra Ravula, Brad M Savall

Bioorg Med Chem Lett· January 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Allyl-Assisted, Cu(I)-Catalyzed Azide-Alkyne Cycloaddition/Allylation Reaction: Assembly of the [1,2,3]Triazolo-4,5,6,7-tetrahydropyridine Core Structure.
Xiaohu Deng, Jimmy Liang, Brett B Allison, Curt Dvorak, Heather McAllister, Brad M Savall

J Org Chem· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators.
Mark S Tichenor, Robin L Thurmond, Jennifer D Venable, Brad M Savall

J Med Chem· September 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, SAR, and Pharmacological Characterization of Brain Penetrant P2X7 Receptor Antagonists.
Brad M Savall, Duncan Wu, Meri De Angelis, Nicholas I Carruthers, Hong Ao

ACS Med Chem Lett· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diaminopyrimidines, diaminopyridines and diaminopyridazines as histamine H4 receptor modulators.
Brad M Savall, Steven P Meduna, Kevin Tays, Hui Cai, Robin L Thurmond

Bioorg Med Chem Lett· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The effect of pK(a) on pyrimidine/pyridine-derived histamine H4 ligands.
Brad M Savall, Steven P Meduna, Jennifer Venable, Jianmei Wei, Russell C Smith

Bioorg Med Chem Lett· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and SAR of 6-alkyl-2,4-diaminopyrimidines as histamine H₄ receptor antagonists.
Brad M Savall, Frank Chavez, Kevin Tays, Paul J Dunford, Jeffery M Cowden

J Med Chem· March 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tricyclic aminopyrimidine histamine H4 receptor antagonists.
Brad M Savall, Laurent Gomez, Frank Chavez, Michael Curtis, Steven P Meduna

Bioorg Med Chem Lett· November 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Triamino pyrimidines and pyridines as histamine H(4) receptor modulators.
Steven P Meduna, Brad M Savall, Hui Cai, James P Edwards, Robin L Thurmond

Bioorg Med Chem Lett· May 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Agonist/antagonist modulation in a series of 2-aryl benzimidazole H4 receptor ligands.
Brad M Savall, James P Edwards, Jennifer D Venable, Daniel J Buzard, Robin Thurmond

Bioorg Med Chem Lett· June 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Cheryl A Grice, Kevin L Tays, Brad M Savall, Jianmei Wei, Christopher R Butler

J Med Chem· July 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Total synthesis of formamicin.
Timothy B Durham, Nicolas Blanchard, Brad M Savall, Noel A Powell, William R Roush

J Am Chem Soc· August 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Total synthesis of the formamicin aglycon, formamicinone.
Brad M Savall, Nicolas Blanchard, William R Roush

Org Lett· February 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Total synthesis of (-)-bafilomycin A(1).
Karl A Scheidt, Thomas D Bannister, Akihiro Tasaka, Michael D Wendt, Brad M Savall

J Am Chem Soc· June 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Highly diastereoselective synthesis of propargylic 1,2-anti-diol derivatives using alpha-alkoxypropargylstannanes.
B M Savall, N A Powell, W R Roush

Org Lett· September 2001

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sound velocity and attenuation in single-crystal C60.
XD Shi, AR Kortan, JM Williams, AM Kini, BM Savall

Phys Rev Lett· February 1992

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis