Publications by authors named "Christopher Rath"

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METASPACE-ML: Context-specific metabolite annotation for imaging mass spectrometry using machine learning.
Bishoy Wadie, Lachlan Stuart, Christopher M Rath, Bernhard Drotleff, Sergii Mamedov

Nat Commun· October 2024

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microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data.
Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender P Gomes, Andres M Caraballo-Rodriguez, Christopher M Rath

Nat Microbiol· February 2024

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A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data.
Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender P Gomes, Andres M Caraballo-Rodriguez, Christopher M Rath

Res Sq· August 2023

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Interplay of Klebsiella pneumoniae and Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis.
Mina Mostafavi, Lisha Wang, Lili Xie, Kenneth T Takeoka, Daryl L Richie, Christopher M Rath

mSphere· October 2018

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Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity.
Colin K Skepper, Robert J Moreau, Brent A Appleton, Bret M Benton, Joseph E Drumm, Christopher M Rath

J Med Chem· April 2018

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Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics.
Christopher M Rath, Bret M Benton, Javier de Vicente, Joseph E Drumm, Mei Geng

ACS Infect Dis· March 2018

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Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606.
Daryl L Richie, Kenneth T Takeoka, Jade Bojkovic, Louis E Metzger, Christopher M Rath

PLoS One· July 2017

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Assessing Antibiotic Permeability of Gram-Negative Bacteria via Nanofluidics.
SoonGweon Hong, Tobias J Moritz, Christopher M Rath, Pramila Tamrakar, Philip Lee

ACS Nano· July 2017

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LpxK Is Essential for Growth of ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates.
Jun-Rong Wei, Daryl L Richie, Mina Mostafavi, Louis E Metzger, Christopher M Rath

mSphere· July 2017

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Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism.
Dustin Dovala, Christopher M Rath, Qijun Hu, William S Sawyer, Steven Shia

Proc Natl Acad Sci U S A· October 2016

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Rapid analysis of protein expression and solubility with the SpyTag-SpyCatcher system.
Dustin Dovala, William S Sawyer, Christopher M Rath, Louis E Metzger

Protein Expr Purif· January 2016

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Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis.
Jade Bojkovic, Daryl L Richie, David A Six, Christopher M Rath, William S Sawyer

J Bacteriol· December 2015

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Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate.
Mostafa E Rateb, Yin Zhai, Emmanuelle Ehrner, Christopher M Rath, Xiaoling Wang

Org Biomol Chem· October 2015

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Molecular cartography of the human skin surface in 3D.
Amina Bouslimani, Carla Porto, Christopher M Rath, Mingxun Wang, Yurong Guo

Proc Natl Acad Sci U S A· April 2015

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Molecular networking as a dereplication strategy.
Jane Y Yang, Laura M Sanchez, Christopher M Rath, Xueting Liu, Paul D Boudreau

J Nat Prod· September 2013

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Data-independent microbial metabolomics with ambient ionization mass spectrometry.
Christopher M Rath, Jane Y Yang, Theodore Alexandrov, Pieter C Dorrestein

J Am Soc Mass Spectrom· August 2013

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Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.
Douglas A Hansen, Christopher M Rath, Eli B Eisman, Alison R H Narayan, Jeffrey D Kittendorf

J Am Chem Soc· July 2013

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Early migration characteristics of a 180° porous-coated cup with 1-mm press fit.
Christoph Stihsen, Christopher Rath, Roman Radl, Ali A Saalabian, Wilfried Materna

Arch Orthop Trauma Surg· May 2013

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Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations.
Christopher M Rath, Theodore Alexandrov, Steven K Higginbottom, Jiao Song, Marcos E Milla

Anal Chem· November 2012

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Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.
Joseph A Chemler, Tonia J Buchholz, Todd W Geders, David L Akey, Christopher M Rath

J Am Chem Soc· May 2012

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The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes.
Christopher M Rath, Pieter C Dorrestein

Curr Opin Microbiol· April 2012

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Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743.
Christopher M Rath, Benjamin Janto, Josh Earl, Azad Ahmed, Fen Z Hu

ACS Chem Biol· November 2011

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Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module.
Yousong Ding, Christopher M Rath, Kyle L Bolduc, Kristina Håkansson, David H Sherman

J Am Chem Soc· September 2011

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Acyl-CoA subunit selectivity in the pikromycin polyketide synthase PikAIV: steady-state kinetics and active-site occupancy analysis by FTICR-MS.
Shilah A Bonnett, Christopher M Rath, Abdur-Rafay Shareef, Joanna R Joels, Joseph A Chemler

Chem Biol· September 2011

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Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.
Tonia J Buchholz, Christopher M Rath, Nicole B Lopanik, Noah P Gardner, Kristina Håkansson

Chem Biol· October 2010

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