Publications by authors named "Kevin DeMent"

Claim this Profile
D
Design and Discovery of a Potent and Selective Inhibitor of Integrin αvβ1.
Mark Sabat, Daniel W Carney, Gloria Hernandez-Torres, Tony S Gibson, Deepika Balakrishna, Kevin DeMent

J Med Chem· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GTP1 metabolic stability assessment: A study of the tau PET tracer [F]GTP1.
Jan Marik, Sharyl Rich, Gauri Deshmukh, Donglu Zhang, Jeff Tinianow, Kevin DeMent

Nucl Med Biol· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.
Alexander M Taylor, Chris Bailey, Lisa D Belmont, Robert Campbell, Nico Cantone, Kevin DeMent

J Med Chem· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey.
Carl Petersson, Xin Zhou, Joerg Berghausen, David Cebrian, Michael Davies, Kevin DeMent

AAPS J· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction to: Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.
Arian Emami Riedmaier, Kevin DeMent, James Huckle, Phil Bransford, Cordula Stillhart

AAPS J· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.
Arian Emami Riedmaier, Kevin DeMent, James Huckle, Phil Bransford, Cordula Stillhart

AAPS J· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors.
Brendan T Parr, Richard Pastor, Benjamin D Sellers, Zhonghua Pei, Firoz A Jaipuri, Kevin Dement

ACS Med Chem Lett· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity.
Naomi S Rajapaksa, Alberto Gobbi, Joy Drobnick, Steven Do, Aleksandr Kolesnikov, Kevin DeMent

ACS Med Chem Lett· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors.
Marian C Bryan, Joy Drobnick, Alberto Gobbi, Aleksandr Kolesnikov, Yongsheng Chen, Kevin DeMent

J Med Chem· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of a mass spectrometry-based tryptophan 2, 3-dioxygenase assay using liver cytosol from multiple species.
Jing Wang, Ryan H Takahashi, Kevin DeMent, Amy Gustafson, Jane R Kenny

Anal Biochem· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Practical strategies when using a stable isotope labeled microtracer for absolute bioavailability assessment: A case study of a high oral dose clinical candidate GDC-0810.
Buyun Chen, Pingping Lu, Dugan Freeman, Yang Gao, Edna Choo, Kevin DeMent

J Pharm Biomed Anal· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2).
Zhonghua Pei, Rohan Mendonca, Lewis Gazzard, Richard Pastor, Leanne Goon, Kevin Dement

ACS Med Chem Lett· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preparation and evaluation of L- and D-5-[F]fluorotryptophan as PET imaging probes for indoleamine and tryptophan 2,3-dioxygenases.
Tang Tang, Herman S Gill, Annie Ogasawara, Jeff N Tinianow, Alexander N Vanderbilt, Kevin DeMent

Nucl Med Biol· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice.
Dong U Lee, Paula Katavolos, Gopinath Palanisamy, Arna Katewa, Charly Sioson, Kevin DeMent

Toxicol Appl Pharmacol· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Use of transgenic mouse models to understand the oral disposition and drug-drug interaction potential of cobimetinib, a MEK inhibitor.
Edna F Choo, Sarah Woolsey, Kevin DeMent, Justin Ly, Kirsten Messick

Drug Metab Dispos· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biotransformation and bioactivation reactions of alicyclic amines in drug molecules.
Jayaprakasam Bolleddula, Kevin DeMent, James P Driscoll, Philip Worboys, Patrick J Brassil

Drug Metab Rev· August 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis