4,218,365 results match your criteria: "Enzymes"

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Targeting glucose-inhibited hippocampal CCK interneurons prevents cognitive impairment in diet-induced obesity.
Taylor Landry, Laura Perrault, David Melville, Zhe Chen, Ya-Dong Li

Neuron· November 2025

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Cholesterol-lowering drug targets reduce risk of dementia: Mendelian randomization and meta-analyses of 1 million individuals.
Liv Tybjærg Nordestgaard, Aimee Hanson, Eleanor Sanderson, Emma Anderson, Venexia Walker

Alzheimers Dement· October 2025

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From Diabetes to Degenerative Diseases: The Multifaceted Action of Metformin.
Lucrezia Irene Maria Campagnoli, Angelica Varesi, Foroogh Fahmideh, Reza Hakimizad, Petra Petkovic

Int J Mol Sci· October 2025

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Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer.
Anna Martling, Ida Hed Myrberg, Mef Nilbert, Henrik Grönberg, Fredrik Granath

September 2025

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Therapeutic Targeting of Oncogene-Induced Transcription-Replication Conflicts in Pancreatic Ductal Adenocarcinoma.
Shanna J Smith, Fan Meng, Robert G Lingeman, Caroline M Li, Min Li

Gastroenterology· September 2025

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A STUB1-CHIC2 complex inhibits CD8 T cells to restrain tumor immunity.
Martin W LaFleur, Lauren E Milling, Priyamvada Prathima, Vivian Li, Ashlyn M Lemmen

Nat Immunol· September 2025

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Lithium deficiency and the onset of Alzheimer's disease.
Liviu Aron, Zhen Kai Ngian, Chenxi Qiu, Jaejoon Choi, Marianna Liang

Nature· September 2025

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Neoadjuvant Osimertinib for Resectable -Mutated Non-Small Cell Lung Cancer.
Jianxing He, Masahiro Tsuboi, Walter Weder, Ke-Neng Chen, Maximilian J Hochmair

J Clin Oncol· September 2025

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Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes.
Declan Whyte, Sophie L Fisher, Christopher G J McKenzie, David Sumpton, Sandeep Dhayade

EMBO Rep· September 2025

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Hepatic miR-93 promotes the pathogenesis of metabolic dysfunction-associated steatotic liver disease by suppressing SIRT1.
Yo Han Lee, Jinyoung Lee, Joonho Jeong, Kieun Park, Bukyung Baik

Metabolism· August 2025

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ST8Sia6 overexpression protects pancreatic β cells from spontaneous autoimmune diabetes in nonobese diabetic mice.
Justin Choe, Paul Belmonte, Sydney Crotts, Thanh Nguyen, David Friedman

J Clin Invest· August 2025

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Age-related dysregulation of proteasome-independent K63 polyubiquitination in the hippocampus and amygdala.
Yeeun Bae, Harshini Venkat, Natalie Preveza, W Keith Ray, Richard F Helm

Neuroscience· August 2025

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Curcumin as an antidote to atrazine on estrogen homeostasis and beyond: mechanistic insights from a targeted literature review.
Patrick J Wright, Jade Ilali, Pengli Bu

Front Endocrinol (Lausanne)· August 2025

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Intra- versus interpersonal emotion regulation: Associations with affect, relationship quality and closeness, and biological markers of stress.
Ashley M Battaglini, Bita Zareian, Joelle LeMoult

J Exp Psychol Gen· July 2025

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Utility of Mechanistic Target of Rapamycin Inhibitors in Cardiac Sarcoidosis.
Donald Richards, Hidesato Fujito, Aakash Shanbhag, Bobak Akhavan, Elizabeth Frame

July 2025

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NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging.
Sabina Chubanava, Iuliia Karavaeva, Amy M Ehrlich, Roger M Justicia, Astrid L Basse

Cell Metab· July 2025

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Double Digest Restriction-Site Associated DNA Sequencing (ddRAD-Seq).
Zenaida V Magbanua, Chuan-Yu Hsu, Olga Pechanova, Mark Arick, Daniel G Peterson

Methods Mol Biol· June 2025

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Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease.
Kiran Musunuru, Sarah A Grandinette, Xiao Wang, Taylor R Hudson, Kevin Briseno

June 2025

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Extracellular exosomal RNAs are glyco-modified.
Sunny Sharma, Xinfu Jiao, Jun Yang, Kelvin Y Kwan, Megerditch Kiledjian

Nat Cell Biol· June 2025

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Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review.
Xianghui Zhao, Peiying Lv, Zixing Cai, Jun Dong, Wenxiang Chen

Front Immunol· June 2025

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Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer.
Jian-Min Yuan, Thomas W Kensler, Sanja Dacic, Douglas J Hartman, Renwei Wang

Cancer Prev Res (Phila)· June 2025

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The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function.
Auburn R Berry, Samuel T Ruzzene, Emily I Ostrander, Kendra N Wegerson, Nathalie C Orozco-Fersiva

J Appl Physiol (1985)· June 2025

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CD38 Coordinates with NF-κB to Promote Cochlear Inflammation in Noise-Induced Hearing Loss: the Protective Effect of Apigenin.
Da Liu, Na Sai, Ying Zhou, Ning Yu, Qing-Qing Jiang

Mol Neurobiol· May 2025

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ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression.
Che-Chia Hsu, Chi-Yun Wang, Rajesh Kumar Manne, Zhen Cai, Vasudevarao Penugurti

Nat Cell Biol· May 2025

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Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE): a multicentre, randomised, controlled trial.
Richard J Bryant, Ioana R Marian, Roxanne Williams, J Francisco Lopez, Claudia Mercader

Lancet Oncol· May 2025

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Clonal hematopoiesis landscape in frequent blood donors.
Darja Karpova, Hector Huerga Encabo, Elisa Donato, Silvia Calderazzo, Michael Scherer

Blood· May 2025

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HDLR-SR-BI Expression and Cholesterol Uptake are Regulated via Indoleamine-2,3-dioxygenase 1 in Macrophages under Inflammation.
Avisankar Chini, Prarthana Guha, Ashcharya Rishi, Nagashree Bhat, Angel Covarrubias

Langmuir· May 2025

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Synergistic Roles of FAHD-1 and PYC-1 in Mitochondrial Function, Behavior, and Longevity in C. elegans.
Riccardo Giaquinta, Andreas Andric, Matthias Scheppach, Alexander K H Weiss

Adv Biol (Weinh)· December 2025

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Novel cinnamic acid-ribavirin conjugates: design, synthesis, antiviral activity against tobacco mosaic virus and mechanistic study.
Min Luo, Chen Chen, Min Xu, Wen-Xin Lv, Yonggui Robin Chi

Pest Manag Sci· December 2025

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The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease.
Annelise E Barron, Jennifer S Lin, Mark I Ryder, Peter Bergman

J Intern Med· December 2025

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BACE1: Biological Functions and Involvement in the Pathophysiology of Alzheimer's Disease and Other Neurological Disorders.
Marija Bartolić, Anita Bosak

Biofactors· December 2025

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Staphylococcal SplA and SplB Serine Protease Allelic Variants Exhibit Different Substrate Specificities.
Felix L Glinka, Katharina Mehnert, Lena Koch, Ole Schmöker, Leif Steil

Chembiochem· December 2025

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Collagen-Based Hydrogel Loaded With Microspheres Encapsulated With Placental Mesenchymal Stem Cells-Derived Exosomes Synergistically Promote Recovery After Spinal Cord Injury in Rats.
Jiwei Zou, Mohd Hasmizam Razali, Zhen Sun, Yang Gao

J Biomed Mater Res B Appl Biomater· January 2026

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Exogenous γ-Aminobutyric Acid (GABA) Alleviates the Trade-Off Between Growth and Andrographolide Accumulation in Andrographis paniculata.
Chu Zhong, Jing Wang, Xiao-Ying Chen, Si Wan, Yan-Fen Huang

Physiol Plant· December 2025

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A comprehensive review on azole-based hydroxamic acid analogs as histone deacetylases (HDACs) inhibitors.
Deepali Shukla, Balaji Wamanrao Matore, Anjali Murmu, Pragya Gawande, Partha Pratim Roy

Future Med Chem· December 2025

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sp. nov. (Spiruroidea: Spirocercidae), a new nematode species in the neotropical felid jaguarundi, (Carnivora: Felidae).
A Rojas, L M Romero-Vega, A Conejo-Chacón, I Hagnauer, A Alfaro-Alarcón

J Helminthol· December 2025

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Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study.
María Salud García-Gutiérrez, Abraham Bailén Torregrosa, Francisco Navarrete, Auxiliadora Aracil-Fernández, Gabriel Rubio

Addiction· December 2025

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Usnic Acid induces dual-pathway apoptosis in SKOV-3 ovarian cancer cells via PARP1 inhibition and MAPK pathway activation.
Mehmet Kürşat Derici, Mine Ensoy, Pelin Mutlu, Demet Cansaran-Duman

Hum Exp Toxicol· December 2025

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COLLAGEN SUPPLEMENTATION IN METABOLIC SYNDROME: A NARRATIVE REVIEW UNRAVELING THE BIOLOGICAL MECHANISMS AND EFFECTS.
Marián Pueyo-Arias, Miguel López-Yoldi, Santiago Navas-Carretero, Carlos J González-Navarro, María A Zulet

Nutr Res Rev· December 2025

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RING-Type E3 Ligase OsRFPH2-6 Ubiquitinates Nuclear Factor Y Subunit OsNF-YA1 to Suppress Rice Immunity.
Yan Bi, Leeza Tariq, Hui Wang, Yuqing Yan, Dayong Li

Mol Plant Pathol· December 2025

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Effect of TGFβ-ITGB6 feedback loop on liver metastasis in SMAD4 wild-type pancreatic cancer.
Yutong Zhao, Cheng Qin, Bangbo Zhao, Zeru Li, Tianyu Li

Chin Med J (Engl)· December 2025

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Multi-Angle Bioactivity Cartography for Computational Screening and Mechanistic Analysis of AChE Inhibitors From Yellow Gastrodia elata.
Ruijun Sun, Yuchi Zhang, Jingying Xu, Ming Chen, Chunming Liu

Arch Pharm (Weinheim)· December 2025

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METTL3-Mediated m6A Modification Facilitates pri-miR-221 Maturation to Regulate Macrophage M1/M2 Polarisation and Immune Inflammation in Rheumatoid Arthritis.
Xiangping Gong, Wei Li, Xiaohui Wu, Lirong Mao

Clin Exp Pharmacol Physiol· January 2026

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Total Synthesis of the TIM-1 IgV Domain via N-to-C Serine/Threonine Ligation Enabled by Knorr Pyrazole Synthesis-Mediated Regeneration of Salicylaldehyde Esters.
Xiaolin Cheng, Zhenquan Sun, Hongxiang Wu, Yisa Xiao, Pengfei Shi

J Am Chem Soc· December 2025

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[Inhibition of -GlcNAc transferase alleviates liver pathological changes in spontaneously obese mice].
Zi-Yang Zhang, Xin-Yu Long, Jia-Yi Zhang, Xiao-Shuang Li, Le-Le Kou

Sheng Li Xue Bao· December 2025

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[Treadmill exercise improves constipation in mice with chronic Parkinson's disease through activating autophagy].
Bi-Hui Nie, Yuan Gao, Xiao-Qian Liu, De-Kun Liu, Xian-Juan Kou

Sheng Li Xue Bao· December 2025

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License to Replicate: Mechanisms of Licensing Eukaryotic Origins for DNA Replication.
Victoria Frisbie, Franziska Bleichert

Bioessays· January 2026

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Effects of Incremental Training on the Physiology and Mucosal Immunity of Adolescent Swimmers.
Ming-Ru Chiang, Chi-Cheng Lu, Katsuhiko Suzuki, Bao-Lien Hung, Hsing-Hao Wang

Eur J Sport Sci· January 2026

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Synthesis, Bioactivity, and Mechanistic Insights of Novel Arecoline-Fused Quinazoline Derivatives as Potential Agents for Controlling Tea Tree Fungal Diseases.
Haixia Tang, Shiyi Liu, Xuan Yang, Dandan Xie, Linhong Jin

J Agric Food Chem· December 2025

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Arabinose-Inducible Univariant Control System (AUCS) for Microbial Production of Proteins, Enzymes, and Metabolites.
Congqiang Zhang, Sudha Shukal

ACS Synth Biol· December 2025

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Effects of resveratrol on CYP450-derived arachidonic acid metabolites and mRNA gene expression in human endothelial HUVEC cells.
Yazun Bashir Jarrar, Mansour Al-Sayed Ahmad, Arwa Althaher, Wesam Nasser, Fatima Khirfan

J Complement Integr Med· December 2025

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Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration.
Zhipeng Deng, Camila B Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji

Adv Healthc Mater· December 2025

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KNDy neurons as an indirect target of insulin-like growth factor-1.
Josiane do N Silva, Ligia M M de Sousa, Maria E de Sousa, Henrique R Vieira, Guilherme A Alves

J Neuroendocrinol· January 2026

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Harnessing Photoenzymatic Systems for Intermolecular C-H Fluorination.
Yu Zhou, Danielle Lawson, Zihan Zhang, Yunling Deng, Hejun Deng

Angew Chem Int Ed Engl· December 2025

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