Proteins

Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2.

Katherine U Gaynor, Marina Vaysburd, Maximilian A J Harman, et al.

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Effect of curcumin on rheumatoid arthritis: a systematic review and meta-analysis.

Haiyang Kou, Lei Huang, Meng Jin, et al.

38 mentions

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Mitochondrial DNA induces nucleus pulposus cell pyroptosis via the TLR9-NF-κB-NLRP3 axis.

Peng Lu, Huayong Zheng, Hao Meng, et al.

11 mentions

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Co-inhibition of TIGIT and PD-1/PD-L1 in Cancer Immunotherapy: Mechanisms and Clinical Trials.

Xianjing Chu, Wentao Tian, Ziqi Wang, et al.

7 mentions

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Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries.

Krista R B Gert, Karin Panser, Joachim Surm, et al.

9 mentions

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Pertuzumab Plus Trastuzumab in Patients With Lung Cancer With Mutation or Amplification: Results From the Targeted Agent and Profiling Utilization Registry Study.

Apar K Ganti, Michael Rothe, Pam K Mangat, et al.

20 mentions

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Buffy coat signatures of breast cancer risk in a prospective cohort study.

Felicia Fei-Lei Chung, Sandra González Maldonado, Amelie Nemc, et al.

10 mentions

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Expanding genotype-phenotype correlations in FOXG1 syndrome: results from a patient registry.

Elise Brimble, Kathryn G Reyes, Kopika Kuhathaas, et al.

4 mentions

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Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function.

Cristiana Iosef, Michael J Knauer, Michael Nicholson, et al.

141 mentions

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Generalized precursor prediction boosts identification rates and accuracy in mass spectrometry based proteomics.

Aaron M Scott, Christofer Karlsson, Tirthankar Mohanty, et al.

7 mentions

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Genomics of cold adaptations in the Antarctic notothenioid fish radiation.

Iliana Bista, Jonathan M D Wood, Thomas Desvignes, et al.

114 mentions

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M1BP is an essential transcriptional activator of oxidative metabolism during Drosophila development.

Gabriela Poliacikova, Marine Barthez, Thomas Rival, et al.

11 mentions

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Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity.

Mansi Arora, Justin Moser, Timothy E Hoffman, et al.

61 mentions

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Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation.

Yong Mi Choi, Dalila Ajjaji, Kaelin D Fleming, et al.

22 mentions

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Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration.

Shunsuke Koga, Michael A Metrick, Lawrence I Golbe, et al.

8 mentions

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Identification of a covert evolutionary pathway between two protein folds.

Devlina Chakravarty, Shwetha Sreenivasan, Liskin Swint-Kruse, et al.

38 mentions

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The blood proteome of imminent lung cancer diagnosis.

12 mentions

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Evolving Management of Low-Density Lipoprotein Cholesterol: A Personalized Approach to Preventing Atherosclerotic Cardiovascular Disease Across the Risk Continuum.

Michael J Wilkinson, Norman E Lepor, Erin D Michos

35 mentions

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Pavement cells distinguish touch from letting go.

Alexander H Howell, Carsten Völkner, Patrick McGreevy, et al.

74 mentions

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Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway.

Hongqi Zhang, Gang Xiang, Jiong Li, et al.

2 mentions

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Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli.

Sourik Dey, Marc Blanch-Asensio, Sanjana Balaji Kuttae, et al.

41 mentions

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Preclinical Efficacy of the Antibody-Drug Conjugate CLDN6-23-ADC for the Treatment of CLDN6-Positive Solid Tumors.

Martina S J McDermott, Neil A O'Brien, Benjamin Hoffstrom, et al.

3 mentions

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Downregulation of cardiac PIASy inhibits Cx43 SUMOylation and ameliorates ventricular arrhythmias in a rat model of myocardial ischemia/reperfusion injury.

Tingting Wang, Jinmin Liu, Chenchen Hu, et al.

103 mentions

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Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells via lipid metabolism regulation at least partly by suppressing the Akt/mTOR/SREBP1 pathway.

Lu-Chang Liang, Lei Zhao, Bo Yu, et al.

2 mentions

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