65,128 results match your criteria: "Proteolysis"

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Dual-Capped Helical Interface Mimics.
Tianxiong Mi, Zhe Gao, Zeynep Mituta, Kevin Burgess

J Am Chem Soc· April 2024

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The proteasome regulates body weight and systemic nutrient metabolism during fasting.
Henning Tim Langer, Samuel R Taylor, Mujmmail Ahmed, Tiffany Perrier, Tanvir Ahmed

Am J Physiol Endocrinol Metab· November 2023

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Glutathione-Scavenging Nanoparticle-Mediated PROTACs Delivery for Targeted Protein Degradation and Amplified Antitumor Effects.
Hai-Jun Liu, Wei Chen, Gongwei Wu, Jun Zhou, Chuang Liu

Adv Sci (Weinh)· June 2023

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Global contribution of pelagic fungi to protein degradation in the ocean.
Eva Breyer, Zihao Zhao, Gerhard J Herndl, Federico Baltar

Microbiome· September 2022

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Light-dependent N-end rule-mediated disruption of protein function in Saccharomyces cerevisiae and Drosophila melanogaster.
Leslie M Stevens, Goheun Kim, Theodora Koromila, John W Steele, James McGehee

PLoS Genet· May 2021

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The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment.
Séverine Lamon, Aimee Morabito, Emily Arentson-Lantz, Olivia Knowles, Grace Elizabeth Vincent

January 2021

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TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.
Dorothea Bestle, Miriam Ruth Heindl, Hannah Limburg, Thuy Van Lam van, Oliver Pilgram

Life Sci Alliance· September 2020

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The opioid effects of gluten exorphins: asymptomatic celiac disease.
Leo Pruimboom, Karin de Punder

J Health Popul Nutr· November 2015

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Sleep and muscle recovery: endocrinological and molecular basis for a new and promising hypothesis.
M Dattilo, H K M Antunes, A Medeiros, M Mônico Neto, H S Souza

Med Hypotheses· August 2011

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Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC-Induced Degradation.
Daniel Schäfer, Cristian Prieto-Garcia, Jianhui Wang, Marcel Heinz, Vigor Matkovic

Angew Chem Int Ed Engl· December 2025

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Targeting KRAS G12D: Advances in Inhibitor Design.
Kaiyin Shi, Amin Li

Thorac Cancer· December 2025

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Recent advances in antitumor indole-chalcone derivatives: a mini review.
Guangyuan Liu, Yawei Han, Yuhao Wei, Pengyu Qian, Yirong Zhou

Eur J Pharmacol· December 2025

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Duet between stress granules and glutathionylation regulates cytosolic redox state to maintain proteostasis in Arabidopsis.
Shuai Zhao, Zhouli Xie, Xiaoyuan Chen, Yabo Shi, Haiwei Li

Mol Plant· December 2025

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Conformation-Dependent Complexation Interactions for a SMARCA2 PROTAC and Cyclodextrin.
Matthew N O'Brien Laramy, José G Napolitano, Yuhui Zhou, David J Russell, Sarah Robinson

Mol Pharm· December 2025

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Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities.
Jianfeng Ge, Shoko Hirosue, Leticia Castillon, Saroor A Patel, Ludovic Wesolowski

EMBO Mol Med· December 2025

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γ-Secretase exosites as targets for substrate-selective lowering of Aβ generation.
Riki Maruyama, Akio Fukumori, Satoru Funamoto, Ken Okada, Shoshin Akamine

Structure· December 2025

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Synthesis and identification of a novel selective USP7 degrader that inhibits the migration of upper gastrointestinal cancer cells without affecting proliferation.
Xu-Bin Ma, Kai Sun, Yuan-Yuan Liu, Liang Wang, Chen-Ran Lu

Eur J Med Chem· December 2025

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Novel PROTACs with polyhedral alkanes as linkers for enhanced ALK degradation in drug-resistant NSCLC.
Dongchen Chu, Huijie Han, Chaochun Wei, Xiaokun Zhang, Hong Yan

Bioorg Med Chem· December 2025

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Pharmacological inhibition of Ubiquitin-Specific Peptidase 10 (USP10) with spautin-1 attenuates adipogenesis through CCAAT/Enhancer-Binding Protein Beta (C/EBPβ) destabilization.
Zolzaya Erdenebileg, Desy Damayanti Simamora, Joong-Kwon Park, Rosana Nogueira, Young Bin Kim

Mol Biomed· December 2025

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Proteolysis Targeting Chimera Loaded Extracellular Vesicles for Developing Triple Negative Breast Cancer Treatment.
Nina Erwin, Umasankar De, Yufeng Xiao, Lei Wang, Chandra K Maharjan

J Extracell Vesicles· December 2025

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Computational Modeling of PROTAC Ternary Complexes as Ensembles Using SILCS-xTAC.
Erik B Nordquist, Mingtian Zhao, Wenbo Yu, Alexander D MacKerell

J Chem Inf Model· December 2025

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Polyanionic Sugars Drastically Affect Assembly of Human Papilloma Virus Virus-Like Particles.
Angela Patterson, Kim Young, MacRyan P Biever, Shelby M Klein, Stephen C Jacobson

ACS Infect Dis· December 2025

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β-Catenin and AMPK/AKT/FOXO Signaling Mediate Doxorubicin-Induced Senescence and Lipid Accumulation in C2C12 Myoblasts.
Chawon Yun, Sou Hyun Kim, Doyoung Kwon, RanJu Woo, Ki Wung Chung

Biomol Ther (Seoul)· December 2025

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Utilizing nanoinducers for precision degradation of bacterial protein to mitigate antibiotic resistance.
Linqi Han, Wenping Huang, Xueting Pan, Ziying Fu, Hao Peng

Nat Commun· December 2025

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Changes in muscle quality of Antarctic krill (Euphausia superba) during refrigerated storage: The role of protein degradation.
Xinyu Zhang, Xiang Ren, Peizi Sun, Yuting Tan, Huihui Zhang

Food Res Int· January 2026

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Thermal processing-driven functional transformations of egg components: Albumen and yolk.
Emmanuel Cobbinah-Sam, Idaresit Ekaette

Food Res Int· January 2026

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Transcriptomics analysis of in vivo Opisthorchis viverrini: Stage-specific gene expression and novel genes with stable expression in mammalian stages for opisthorchiasis intervention.
Waraporn Taweesin, Siriyakorn Kulwong, Wassana Jamnongkan, Wichit Taron, Autchasai Siriprayong

PLoS Negl Trop Dis· December 2025

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Emergent eukaryotic directional sensing via receptor degradation and diffusion.
Andrew Goetz, Purushottam Dixit

Proc Natl Acad Sci U S A· December 2025

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Uncovering the potential virulence factors of emerging pathogens using AI/ML-based tools: a case study in .
Peter F Farag, Karema S Abdel-Monem, Hibah M Albasri, Areej A Alhhazmi, Rana H Ismail

Front Cell Infect Microbiol· December 2025

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Efficient production of fully active, SARS-CoV-2-priming, wildtype TMPRSS2 ectodomain via co-expression of HAI-2 allows for both auto- and cross-activation mechanisms.
Barbara Végh, Andrea Kocsis, József Dobó, Júlia Balczer, Bence Kiss

Biochem J· December 2025

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Identification of N-tert-butyloxycarbonyl protected amino acids as novel hydrophobic tags to induce targeted protein degradation.
Hui Sun, Xueyi Luo, Hengjie Hu, Cong Li, Cheng Lyu

Eur J Med Chem· December 2025

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Comparative evaluation of LAB proteolytic activities in soy-based dairy alternatives and bovine milk for selecting plant-based food starter strains.
Joanna Ivy Irorita Fugaban, Steffen Yde Bak, Pascal Fourcassie, Claus Heiner Bang-Berthelsen, Egon Bech Hansen

Int J Food Microbiol· December 2025

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"The RAS Dam Has Broken".

Cancer Discov· December 2025

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Development of Cathepsin B-Responsive GalNAc-PROTACs for Hepatocyte-Targeting Protein Degradation.
Yunhua Peng, Tao Li, Donghua Liu, Wenxin Li, Yimeng Zhang

J Med Chem· December 2025

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A Facile Protocol for C(sp)-C(sp) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands.
Anita Maksutova, Thomas M Geiger, Lorenzo Cianni, Dominika E Pieńkowska, Jan Gerhartz

ChemMedChem· December 2025

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Exposing Hidden Binding Pockets in Cereblon: His378 Conformational Dynamics Inform Novel Ligand Design.
Jiangnan Du, Cunhong Luo, Jin Feng, Xianqiang Sun, Yaozong Li

J Phys Chem B· December 2025

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