Publications by authors named "John Fay"

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Biomarkers.
Wang Yuchuan, Helen J Mitchell, Susi Lee, Zhizhen Zeng, Patricia J Miller, John F Fay

Alzheimers Dement· December 2025

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Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling.
Nadine Alvarez, Gregory C Adam, John A Howe, Vijeta Sharma, Matthew D Zimmerman, John F Fay

Viruses· July 2024

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Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.
Valerie W Shurtleff, Mark E Layton, Craig A Parish, James J Perkins, John D Schreier, John F Fay

J Med Chem· March 2024

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Virtual screening for early identification of potent and selective histone deacetylase 6 inhibitor series.
Shawn J Stachel, Deping Wang, Anthony T Ginnetti, Shahriar Niroomand, Lei Ma, John F Fay

Bioorg Med Chem Lett· October 2023

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Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1.
Carl J Balibar, Daniel J Klein, Beata Zamlynny, Tracy L Diamond, Zhiyu Fang, John F Fay

Sci Transl Med· February 2023

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A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Keith P Moore, Adam G Schwaid, Matthew Tudor, Sangho Park, Douglas C Beshore, John F Fay

ACS Chem Biol· September 2022

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Using geographic information systems to characterize food environments around historically black colleges and universities: Implications for nutrition interventions.
Helene Vilme, Christopher J Paul, Naomi N Duke, Santiba D Campbell, Derrick Sauls, John P Fay

J Am Coll Health· April 2022

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Caregiving in Quarantine: Evaluating the Impact of the Covid-19 Pandemic on Adult Child Informal Caregivers of a Parent.
Jesse Archer, Wendy Reiboldt, Maria Claver, John Fay

Gerontol Geriatr Med· January 2021

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Leveraging Big Data Towards Functionally-Based, Catchment Scale Restoration Prioritization.
John P Lovette, Jonathan M Duncan, Lindsey S Smart, John P Fay, Lydia P Olander

Environ Manage· December 2018

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The identification of a novel lead class for phosphodiesterase 2 inhibition by fragment-based drug design.
Ashley B Forster, Pravien Abeywickrema, Jaime Bunda, Christopher D Cox, Tamara D Cabalu, John Fay

Bioorg Med Chem Lett· December 2017

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Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
Christopher J Bungard, Peter D Williams, Jurgen Schulz, Catherine M Wiscount, M Katharine Holloway, John F Fay

ACS Med Chem Lett· December 2017

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Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
Christopher J Bungard, Peter D Williams, Jeanine E Ballard, David J Bennett, Christian Beaulieu, John F Fay

ACS Med Chem Lett· July 2016

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How many mountains can we mine? Assessing the regional degradation of Central Appalachian rivers by surface coal mining.
Emily S Bernhardt, Brian D Lutz, Ryan S King, John P Fay, Catherine E Carter

Environ Sci Technol· August 2012

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Community Markets for Conservation (COMACO) links biodiversity conservation with sustainable improvements in livelihoods and food production.
Dale Lewis, Samuel D Bell, John Fay, Kim L Bothi, Lydiah Gatere

Proc Natl Acad Sci U S A· August 2011

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Discovery of 3-substituted aminocyclopentanes as potent and orally bioavailable NR2B subtype-selective NMDA antagonists.
Mark E Layton, Michael J Kelly, Kevin J Rodzinak, Philip E Sanderson, Steven D Young, John F Fay

ACS Chem Neurosci· July 2011

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Novel CGRP receptor antagonists from central amide replacements causing a reversal of preferred chirality.
Michael R Wood, Kathy M Schirripa, June J Kim, Rodney A Bednar, John F Fay

Bioorg Med Chem Lett· November 2010

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Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist.
Christopher A Salvatore, Eric L Moore, Amy Calamari, Jacquelynn J Cook, Maria S Michener, John F Fay

J Pharmacol Exp Ther· April 2010

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Identification of potent, highly constrained CGRP receptor antagonists.
Craig A Stump, Ian M Bell, Rodney A Bednar, John F Fay, Steven N Gallicchio

Bioorg Med Chem Lett· April 2010

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Discovery of MK-3207: A Highly Potent, Orally Bioavailable CGRP Receptor Antagonist.
Ian M Bell, Steven N Gallicchio, Michael R Wood, Amy G Quigley, Craig A Stump, John F Fay

ACS Med Chem Lett· April 2010

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Novel CGRP receptor antagonists through a design strategy of target simplification with addition of molecular flexibility.
Michael R Wood, Kathy M Schirripa, June J Kim, Amy G Quigley, Craig A Stump, John F Fay

Bioorg Med Chem Lett· October 2009

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The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists.
Ian M Bell, Rodney A Bednar, Halea A Corcoran, John F Fay, Steven N Gallicchio

Bioorg Med Chem Lett· August 2009

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The discovery of highly potent CGRP receptor antagonists.
Craig A Stump, Ian M Bell, Rodney A Bednar, Joseph G Bruno, John F Fay

Bioorg Med Chem Lett· January 2009

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Potent benzimidazolone-based CGRP receptor antagonists.
Cory R Theberge, Rodney A Bednar, Ian M Bell, Halea A Corcoran, John F Fay

Bioorg Med Chem Lett· December 2008

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Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine.
Christopher A Salvatore, James C Hershey, Halea A Corcoran, John F Fay, Victor K Johnston

J Pharmacol Exp Ther· February 2008

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Climate change, elevational range shifts, and bird extinctions.
Cagan H Sekercioglu, Stephen H Schneider, John P Fay, Scott R Loarie

Conserv Biol· February 2008

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