4,218,757 results match your criteria: "Enzymes"

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Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice.
Zhihui Zhang, Xiao Tian, J Yuyang Lu, Kathryn Boit, Julia Ablaeva

September 2023

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Linking Hypothermia and Altered Metabolism with TrkB Activation.
Okko Alitalo, Gemma González-Hernández, Marko Rosenholm, Piia Kohtala, Nobuaki Matsui

ACS Chem Neurosci· September 2023

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cGAS-STING signaling in cell death: Mechanisms of action and implications in pathologies.
Yifan Xu, Chen Chen, Zhiyong Liao, Pinglong Xu

Eur J Immunol· September 2023

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Photoactivated DNA Assembly and Disassembly for On-Demand Activation and Termination of cGAS-STING Signaling.
Fangzhi Yu, Xiangfei Li, Jian Zhao, Yuliang Zhao, Lele Li

August 2023

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Supplementation with spinach-derived thylakoid augments the benefits of high intensity training on adipokines, insulin resistance and lipid profiles in males with obesity.
Ayoub Saeidi, Mohammad Amin Saei, Behnam Mohammadi, Hamid Reza Akbarzadeh Zarei, Morvarid Vafaei

Front Endocrinol (Lausanne)· August 2023

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Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma.
Ingo K Mellinghoff, Martin J van den Bent, Deborah T Blumenthal, Mehdi Touat, Katherine B Peters

N Engl J Med· August 2023

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Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target.
Kai Wang, Zhiwei Zhang, Jing Hang, Jia Liu, Fusheng Guo

Science· August 2023

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Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import.
Jacob R Mann, Elizabeth D McKenna, Darilang Mawrie, Vasileios Papakis, Francesco Alessandrini

Sci Adv· August 2023

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Ensifentrine, a Novel Phosphodiesterase 3 and 4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease: Randomized, Double-Blind, Placebo-controlled, Multicenter Phase III Trials (the ENHANCE Trials).
Antonio Anzueto, Igor Z Barjaktarevic, Thomas M Siler, Tara Rheault, Thomas Bengtsson

Am J Respir Crit Care Med· August 2023

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Tumor Mutational Burden in Real-World Patients With Pancreatic Cancer: Genomic Alterations and Predictive Value for Immune Checkpoint Inhibitor Effectiveness.
Julia C F Quintanilha, Michael H Storandt, Ryon P Graf, Gerald Li, Rachel Keller

JCO Precis Oncol· July 2023

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Discovering functionally important sites in proteins.
Matteo Cagiada, Sandro Bottaro, Søren Lindemose, Signe M Schenstrøm, Amelie Stein

Nat Commun· July 2023

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Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment.
Zhijun Wang, So Yeon Kim, Wei Tu, Jieun Kim, Alexander Xu

Cell Metab· July 2023

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The crucial role and mechanism of insulin resistance in metabolic disease.
Xuefei Zhao, Xuedong An, Cunqing Yang, Wenjie Sun, Hangyu Ji

Front Endocrinol (Lausanne)· July 2023

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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz

Nat Commun· July 2023

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AXL/Gas6 signaling mechanisms in the hypothalamic-pituitary-gonadal axis.
Pardis Mohammadzadeh, Gregory C Amberg

Front Endocrinol (Lausanne)· July 2023

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Longitudinal multi-omics study of palbociclib resistance in HR-positive/HER2-negative metastatic breast cancer.
Yeon Hee Park, Seock-Ah Im, Kyunghee Park, Ji Wen, Kyung-Hun Lee

Genome Med· July 2023

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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation.
Alessia Calcagni', Leopoldo Staiano, Nicolina Zampelli, Nadia Minopoli, Niculin J Herz

Nat Commun· July 2023

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Rank-ordering of known enzymes as starting points for re-engineering novel substrate activity using a convolutional neural network.
Vikas Upadhyay, Veda Sheersh Boorla, Costas D Maranas

Metab Eng· July 2023

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High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors.
Cheng-Kai Shiau, Lina Lu, Rachel Kieser, Kazutaka Fukumura, Timothy Pan

Nat Commun· July 2023

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MicroRNA 483-3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis.
Ermes Candiello, Gigliola Reato, Federica Verginelli, Gennaro Gambardella, Antonio D Ambrosio

Mol Oncol· July 2023

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ATPase activity of DFCP1 controls selective autophagy.
Viola Nähse, Camilla Raiborg, Kia Wee Tan, Sissel Mørk, Maria Lyngaas Torgersen

Nat Commun· July 2023

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Neurodegenerative disease after hematopoietic stem cell transplantation in metachromatic leukodystrophy.
Murtadha Al-Saady, Shanice Beerepoot, Bonnie C Plug, Marjolein Breur, Hristina Galabova

July 2023

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Cold exposure protects against medial arterial calcification development via autophagy.
Fu-Xing-Zi Li, Jun-Jie Liu, Feng Xu, Su-Kang Shan, Ming-Hui Zheng

J Nanobiotechnology· July 2023

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Architecture of a complete Bce-type antimicrobial peptide resistance module.
Natasha L George, Benjamin J Orlando

Nat Commun· July 2023

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KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition.
Jing Xu, Ailing Zhong, Shan Zhang, Mei Chen, Lanxin Zhang

Adv Sci (Weinh)· July 2023

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Bone marrow mesenchymal stem cell-derived exosomes miR-202-5p inhibited pyroptosis to alleviate lung ischemic-reperfusion injury by targeting CMPK2.
Zhi-Lu Sun, Ting You, Bi-Hong Zhang, Yu Liu, Jing Liu

Kaohsiung J Med Sci· July 2023

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Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes.
Siddhartha Dutta, Rima B Shah, Shubha Singhal, Sudeshna Banerjee Dutta, Sumit Bansal

Drug Des Devel Ther· July 2023

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UBE2I promotes immune infiltration and tumor progression in thyroid cancer and modulates hnRNPA2B1 SUMOylation.
Jinmiao Wang, Minghan Qiu, Li Dong, Jie Hao, Ying Gao

J Biol Chem· December 2025

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N-linked glycosylation plays an essential role in the stability and function of tissue-nonspecific alkaline phosphatase.
Diana Atanasova, Ali Saad Kusay, Lavanya Moparthi, Stefan Koch, Mathias Haarhaus

J Biol Chem· December 2025

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The biosynthesis of N-acylated tryptazolone in Mycobacterium tuberculosis and related bacteria.
Julia Kleetz, Jason C Grigg, Adam A Hassan, Adriana Ibtisam, Janine N Copp

J Biol Chem· December 2025

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Emergence of cefiderocol resistance mediated by bla overexpression and FptA mutations in clinical Carbapenem-Resistant Pseudomonas aeruginosa isolates.
Yanghua Xiao, Jingwen Zhang, Feng Nie, Ping Li, Keyi Li

Clin Microbiol Infect· December 2025

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Inhibition of SCD1 attenuates neuroinflammation and brain injury after cerebral ischemia-reperfusion.
Shuangkai Li, Xiang Li, Lu Peng, Haojie Ding, Xuan Shi

Brain Res Bull· December 2025

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The elevated plasma levels of Claudin-5 are associated with peripheral inflammatory activity in patients with major depressive disorder.
Longhai Wu, Feng Wu, Mengxue Li, Yilin Liu, Siqi Wang

J Affect Disord· December 2025

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The advances of strategies and technologies in high-throughput microbial culturomics.
Zheng-Hui Li, Shuang Li, Hai-Bo Chen, Yi-Zhi Ji, Chong Zhang

Biotechnol Adv· December 2025

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Antibiotic Resistance Crisis: From Bacterial Bioprospecting to Artificial Intelligence.
I C Cunha-Ferreira, C S Vizzotto, J Peixoto, R H Krüger

Environ Microbiol Rep· December 2025

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Discovery and optimization of novel and potent allosteric HIV-1 integrase inhibitors with a spiro[indene] moiety.
Kaoru Adachi, Tomoyuki Manabe, Takayuki Yamasaki, Akira Suma, Yosuke Ogoshi

Bioorg Med Chem· December 2025

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New pyrazolo[1,5-a]pyrimidine derivatives as potential CDK2 inhibitors and apoptosis-driven antiproliferative agents.
Ahmed Abd El-Hamed El-Rahmany, Nadia A Khalil, Mohamed S Nafie, Wagdy M Eldehna, Hatem A Abdel-Aziz

Bioorg Med Chem· December 2025

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Evidence for priming-enhanced microbial degradation of polycyclic aromatic hydrocarbons in marine sediments.
Cristóbal Castillo-Ilabaca, Gerdhard L Jessen, Mario Aranda, Camila Fernández, Laurence Méjanelle

Mar Pollut Bull· December 2025

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Inhibition of NAMPT targets DNA damage response to sensitize alkylating chemotherapy in TP53 mutant mantle cell lymphoma.
Na Li, Yicen Liu, Linna Zhang, Saisai Guo, Zhihao Wu

Blood Adv· December 2025

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CRESTONE: A Phase II Study of the Efficacy and Safety of the HER3 Monoclonal Antibody, Seribantumab, in Solid Tumors With Neuregulin-1 () Fusions.
Tejas Patil, Jessica J Lin, Parneet K Cheema, Daniel R Carrizosa, Mark E Burkard

JCO Precis Oncol· August 2025

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Concordance of Oncotype DX Breast Recurrence Score Assay Results Between Paired Core Needle Biopsy and Surgical Excision Specimens in Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative, Early-Stage Breast Cancer.
Aziza Nassar, Jodi Carter, Paige Innis, Andrea Pingitore Blacklock, Jennifer Racz

JCO Precis Oncol· August 2025

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Exploring the Role of LINC00115 in Esophageal Squamous Cell Carcinoma: Insights Into JAK1/STAT3 Pathway Activation and Metastatic Potential.
Yanyan Yu, Xiaolong Wang, Mengyao Wang, Li Li, Haitao Wei

JCO Precis Oncol· August 2025

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Small-molecule inhibition of γ-glutamyl carboxylase reveals a novel anticoagulant strategy.
Guomin Shen, Dan Song, Shixin Li, Xuejie Chen, Catherine E Richter

Blood Adv· December 2025

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Biosynthesis of 17-Carbon Terpenoids in Bacteria.
Yao-Tao Duan, Chi Zhang, Aikaterini Koutsaviti, Mohamed A Tammam, Maria Harizani

J Am Chem Soc· December 2025

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A conserved hub protein required for peptidoglycan remodeling and cell division in .
Brent W Simpson, Amanda B McLean, M Stephen Trent

Proc Natl Acad Sci U S A· December 2025

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Multiplex mapping of protein-protein interaction interfaces.
Jingxuan He, Ling-Nan Zou, Vidhi Pareek, Stephen J Benkovic

Proc Natl Acad Sci U S A· December 2025

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Why Genetics Can't Be Ignored in Secondary Stroke Prevention: The Challenge in Asia.
Anushika Raheja, Deidre Anne De Silva, Kaavya Narasimhalu

Stroke· January 2026

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Design, Synthesis, and Anticancer Activity of Novel Isocryptolepine "Aza" Type Acyl Thiourea Derivatives via Combined Experimental and Computational Approach.
Ammara Fayyaz, Syeda Abida Ejaz, Atteeque Ahmed, Pervaiz Ali Channar, Saira Afzal

Biosci Rep· December 2025

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Effects of combination therapy of a CDK4/6 and MEK inhibitor in diffuse midline glioma preclinical models.
Yusuke Tomita, Gabrielle Link, Yi Ge, Emma R H Gold, Anna Racanelli

PLoS One· December 2025

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Serum proteomics mirrors the histopathological changes underlying different etiologies of primary mitral valve disease.
Amaia Garcia-Peña, Jaime Ibarrola, Marina Segur, Adela Navarro, Alba Sádaba

Biosci Rep· December 2025

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Substrate Conformational Switch Governs Selective C-S Bond Formation by P450 CxnD.
Yakun Fan, Shengheng Yan, Binju Wang

J Phys Chem B· December 2025

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CDK7-CDK11 axis in spliceosome regulation and pre-mRNA splicing.
Michal Rájecký, Pavla Gajdušková, Peter Maník, Milan Hluchý, Eva Hegedűsová

Nucleic Acids Res· November 2025

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DNA extrusion size determines pathway choice during CAG repeat expansion.
Mayuri Bhatia, Ashutosh S Phadte, Anna Lakhina, Anthony R Monte Carlo Iii, Sarah Barndt

Nucleic Acids Res· November 2025

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A 5'-UTR cis-acting RNA element targeted by RNase III is essential for DNA simple sequence repeat-dependent phase variation in Haemophilus influenzae.
Beatriz Rapún-Araiz, Begoña Euba, Joshua C Mell, Alejandro Toledo-Arana, Junkal Garmendia

Nucleic Acids Res· November 2025

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