Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import.
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Enzymes
1,132 articles with social media discussions tracked by PubHawk in this topic.
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Ensifentrine, a Novel Phosphodiesterase 3 and 4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease: Randomized, Double-Blind, Placebo-controlled, Multicenter Phase III Trials (the ENHANCE Trials).
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Supplementation with spinach-derived thylakoid augments the benefits of high intensity training on adipokines, insulin resistance and lipid profiles in males with obesity.
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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
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AXL/Gas6 signaling mechanisms in the hypothalamic-pituitary-gonadal axis.
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Longitudinal multi-omics study of palbociclib resistance in HR-positive/HER2-negative metastatic breast cancer.
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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation.
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Rank-ordering of known enzymes as starting points for re-engineering novel substrate activity using a convolutional neural network.
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High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors.
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MicroRNA 483-3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis.
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ATPase activity of DFCP1 controls selective autophagy.
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Neurodegenerative disease after hematopoietic stem cell transplantation in metachromatic leukodystrophy.
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Tumor Mutational Burden in Real-World Patients With Pancreatic Cancer: Genomic Alterations and Predictive Value for Immune Checkpoint Inhibitor Effectiveness.
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Discovering functionally important sites in proteins.
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Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment.
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The crucial role and mechanism of insulin resistance in metabolic disease.
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Cold exposure protects against medial arterial calcification development via autophagy.
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Architecture of a complete Bce-type antimicrobial peptide resistance module.
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KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition.
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Bone marrow mesenchymal stem cell-derived exosomes miR-202-5p inhibited pyroptosis to alleviate lung ischemic-reperfusion injury by targeting CMPK2.
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Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes.
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H generated by fermentation in the human gut microbiome influences metabolism and competitive fitness of gut butyrate producers.
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Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity.
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Skin Pigmentation Types, Causes and Treatment-A Review.
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