207,737 results match your criteria: "Lactones"

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Rapamycin, Not Metformin, Mirrors Dietary Restriction-Driven Lifespan Extension in Vertebrates: A Meta-Analysis.
Edward R Ivimey-Cook, Zahida Sultanova, Alexei A Maklakov

Aging Cell· September 2025

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What is the clinical evidence to support off-label rapamycin therapy in healthy adults?
Jacob M Hands, Michael S Lustgarten, Leigh A Frame, Bradley Rosen

Aging (Albany NY)· August 2025

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The geroprotectors trametinib and rapamycin combine additively to extend mouse healthspan and lifespan.
Lisonia Gkioni, Tobias Nespital, Maarouf Baghdadi, Carolina Monzó, Jitin Bali

Nat Aging· July 2025

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Geographic and age variations in mutational processes in colorectal cancer.
Marcos Díaz-Gay, Wellington Dos Santos, Sarah Moody, Mariya Kazachkova, Ammal Abbasi

Nature· July 2025

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Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project.
Amanda E Coleman, Kate E Creevy, Rozalyn Anderson, May J Reed, Virginia R Fajt

Geroscience· June 2025

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Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer.
Bhupesh Kumar Thakur, Yann Malaise, Saurav Roy Choudhury, Anna Neustaeter, Williams Turpin

Nat Microbiol· April 2025

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Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results.
Mauricio Moel, Girish Harinath, Virginia Lee, Andy Nyquist, Stefanie L Morgan

Aging (Albany NY)· April 2025

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Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial.
William F Fearon, Frederik M Zimmermann, Victoria Y Ding, Kuniaki Takahashi, Zsolt Piroth

Lancet· April 2025

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Sodium Zirconium Cyclosilicate for Management of Hyperkalemia During Spironolactone Optimization in Patients With Heart Failure.
Mikhail N Kosiborod, David Z I Cherney, Akshay S Desai, Jeffrey M Testani, Subodh Verma

J Am Coll Cardiol· March 2025

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Colchicine in Acute Myocardial Infarction.
Sanjit S Jolly, Marc-André d'Entremont, Shun Fu Lee, Rajibul Mian, Jessica Tyrwhitt

N Engl J Med· February 2025

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A single-center, double-blind, randomized, placebo-controlled, two-arm study to evaluate the safety and efficacy of once-weekly sirolimus (rapamycin) on muscle strength and endurance in older adults following a 13-week exercise program.
Brad Stanfield, Matt Kaeberlein, Brian Leroux, Julie Jones, Ruth Lucas

Trials· October 2024

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Medications for Obesity: A Review.
Kimberly A Gudzune, Robert F Kushner

August 2024

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mTORC1 activation in presumed classical monocytes: observed correlation with human size variation and neuropsychiatric disease.
Karl Berner, Naci Oz, Alaattin Kaya, Animesh Acharjee, Jon Berner

Aging (Albany NY)· July 2024

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Cnicin promotes functional nerve regeneration.
Philipp Gobrecht, Jeannette Gebel, Marco Leibinger, Charlotte Zeitler, Zhendong Chen

Phytomedicine· July 2024

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Effect of Spironolactone on Kidney Function in Kidney Transplant Recipients (the SPIREN trial): A Randomized Placebo-Controlled Clinical Trial.
Line A Mortensen, Bente Jespersen, Anne Sophie L Helligsoe, Birgitte Tougaard, Donata Cibulskyte-Ninkovic

Clin J Am Soc Nephrol· June 2024

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The Detrimental Effect of Pre-Treatment with Ivermectin on Myocardial Ischemia.
Sara Cheraghi, Shabnam Babataheri, Hamid Soraya

Pharmacology· January 2024

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Systemic Therapy for Tumor Control in Metastatic Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors: ASCO Guideline.
Jaydira Del Rivero, Kimberly Perez, Erin B Kennedy, Erik S Mittra, Namrata Vijayvergia

November 2023

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Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hosts.
Margaret Veitch, Kimberly Beaumont, Rebecca Pouwer, Hui Yi Chew, Ian H Frazer

J Immunother Cancer· September 2023

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Impact of antibiotics on gut microbiome composition and resistome in the first years of life in low- to middle-income countries: A systematic review.
Charlie C Luchen, Mwelwa Chibuye, Rene Spijker, Michelo Simuyandi, Caroline Chisenga

PLoS Med· June 2023

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Targeting the biology of aging with mTOR inhibitors.
Joan B Mannick, Dudley W Lamming

June 2023

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Can Ivermectin kill Sarcoptes scabiei during the molting process?
Shenrui Feng, Minmin Shi, Zhijuan Yin, Wenda Di, Jacques Guillot

PLoS Negl Trop Dis· May 2023

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Clinical differences in sirolimus treatment with low target levels between children and adults with vascular malformations - A nationwide trial.
Veroniek E M Harbers, Lilly G J M Zwerink, Gerard A Rongen, Willemijn M Klein, Carine J M van der Vleuten

Clin Transl Sci· May 2023

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Quantitative and temporal measurement of dynamic autophagy rates.
Nitin Sai Beesabathuni, Soyoon Park, Priya S Shah

Autophagy· April 2023

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The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris.
Jeffrey M Rybak, Christina A Cuomo, P David Rogers

December 2022

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SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells.
Hanjun Zhao, Lu Lu, Zheng Peng, Lin-Lei Chen, Xinjin Meng

Emerg Microbes Infect· December 2022

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Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice.
Randy Strong, Richard A Miller, Catherine J Cheng, James F Nelson, Jonathan Gelfond

Aging Cell· December 2022

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AGA Clinical Practice Guideline on Pharmacological Interventions for Adults With Obesity.
Eduardo Grunvald, Raj Shah, Ruben Hernaez, Apoorva Krishna Chandar, Octavia Pickett-Blakely

Gastroenterology· November 2022

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Exogenous γ-Aminobutyric Acid (GABA) Alleviates the Trade-Off Between Growth and Andrographolide Accumulation in Andrographis paniculata.
Chu Zhong, Jing Wang, Xiao-Ying Chen, Si Wan, Yan-Fen Huang

Physiol Plant· December 2025

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[Inhibition of activation of astrocytes in dorsal hippocampal CA1 relieves lipopolysaccharide-induced cognitive impairment].
Si-Qi Jing, Ying Zhang, Wei-Guo Shi, Kun Tong, Guan-Xiang Kong

Sheng Li Xue Bao· December 2025

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Association Between Atopic Dermatitis and Contact Sensitization: An Updated Systematic Review and Meta-Analysis.
Mikkel Bak Jensen, Christoffer Kursawe Larsen, Carsten R Hamann, Jeanne Duus Johansen, Anna Sophie Quaade

Contact Dermatitis· December 2025

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Changes in Contact Dermatitis Allergen Profile in Chronic Actinic Dermatitis: Results From a Single Centre.
Ying Xin Teo, Louise Cunningham, Hiva Fassihi, Robert Sarkany, Ian R White

Contact Dermatitis· December 2025

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Synergistic effects of new lactone polyketides from an endophytic fungus Phomopsis sp. XP-8 with antibiotics.
Hao Ren, Yamei Miao, Desire Girimpuhwe, Jianjin Guo, Shuxian Ge

Fitoterapia· December 2025

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Cumambrin A from Chrysanthemum boreale attenuates inflammation and oxidative stress through TRIF-dependent signaling inhibition and Nrf2/HO-1 pathway activation.
Dong Hyun Moon, So-Ri Son, Sung Chul Jang, Jaeho Han, Dae Sik Jang

J Ethnopharmacol· December 2025

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Fabrication of Double-Network Hydrogel Based on N,O-carboxymethyl chitosan, Aldehyde Hyaluronate, and Alginate for 3D Bio-Ink Applications.
Binh Thanh Vu, Tuan-Ngan Tang, Dai-Tin Luong, Thao Thi-Phuong Nguyen, Yen-Nhi Ha-Nguyen

Macromol Biosci· December 2025

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Isolating a novel quorum quenching strain based on carbon source adaptability for bioaugmentation under different carbon source conditions.
Jun Li, Yanan Cui, Fan Yang, Yanxue Pei, Muchen Yin

Bioresour Technol· December 2025

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Vietnamese herbal extracts exhibit potent antibacterial activity against Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease in shrimp aquaculture.
Nguyen Thi Truc Linh, Pham Thi Hai Ha, Hong Mong Huyen, Do-Hyung Kim, Nguyen Thanh Luan

J Invertebr Pathol· December 2025

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Mosquito-disseminated diflubenzuron and spinosad as alternatives to mosquito-disseminated pyriproxyfen: a proof-of-concept, blind, controlled comparison in experimental cagesFIRST REVIEW ROUND - REVIEWERS COMMENTSAUTHORS RESPONSE TO REVIEWERSREVIEWERS COMMENTSREVIEWERS COMMENTS.
Gabriela Brandina Aquino de Abreu, Ayrton Sena Gouveia, Francisco Augusto da Silva Ferreira, José Joaquín Carvajal-Cortés, Cláudia Torres Codeço

Mem Inst Oswaldo Cruz· December 2025

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Evaluation of comparative efficacy of Prowill disinfectant, Astragalus root extract, and ivermectin against avian coronavirus in chicken embryo model.
O Ardicli, F O Cöven, A Nalbantsoy, F Cöven, J Abbass

Pol J Vet Sci· December 2025

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Buruli ulcer.
Rie R Yotsu, Rachel E Simmonds, Dziedzom K de Souza, Richard Odame Phillips, Yaw Ampem Amoako

Nat Rev Dis Primers· December 2025

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Efficacy of fourteen-day once-daily vonoprazan-based quadruple therapy for Helicobacter pylori in high clarithromycin-resistance regions (ONCE-VONO Trial).
Saran Sukkamolsantiporn, Phubordee Bongkotvirawan, Soonthorn Chonprasertsuk, Bubpha Pornthisarn, Sith Siramolpiwat

Sci Rep· December 2025

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Dual functionality of phosphates in a micellar casein concentrate: reconstitution enhancement while tailoring acid-induced gel structural properties.
Yi-Fang Gao, Si-Yi Han, Hong-Fu Zhao, Ying-Hua Zhang

Food Res Int· January 2026

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Enhanced VOCs adsorption mechanism on biochar synthesized by one-step molten salt thermal treatment: Experimental and DFT insights.
Shuaijie Yu, Shuai Li, Hongyun Hu, Linxia Gao, Yongda Huang

J Environ Manage· December 2025

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Marked Reduction in Tacrolimus and Everolimus Blood Levels Associated With Sotorasib: A Critical Drug Interaction in a Kidney Transplant Recipient.
Neriman Sila Koç, Mehmet Deniz Ayli

Exp Clin Transplant· November 2025

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Photoinduced, Chemoselective γ-Alkylation of 2-Silyloxyfurans with α-Bromoketones: A Rapid Entry to Chiral ε-Keto-γ-Butenolides.
Debora Guazzetti, Luca Aimi, Enrico Marcantonio, Giovanni Maria Siciliano, Kelly Bugatti

Chemistry· December 2025

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Induction of antigen-specific regulatory T cells by engineered extracellular vesicles.
Shota Imai, Kanto Nagamori, Uryo Onishi, Xiabing Lyu, Iriya Fujitsuka

Drug Deliv· December 2025

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Hochst. (Combretaceae): Medicinal Uses, Phytochemistry and Pharmacological Properties.
Alfred Maroyi

Pak J Biol Sci· December 2025

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Omega-3 fatty acids modulate acetamiprid and emamectin benzoate-induced testicular toxicity in rats by modulating Nrf2/NFkB pathway and apoptotic signaling.
Fatma Mohamady El-Demerdash, Mohamed Yousef Fayed, Ehab Moustafa Tousson, Raghda Ahmed El-Sayed

Sci Rep· December 2025

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Ginkgolide C Improves Cardiac Function and Ameliorates Myocardial Ischemia/Reperfusion Injury by Regulating PI3K/Akt Pathway.
Y Hao, J Wu, Z Gong, W Zhou, Z Wang

Physiol Res· December 2025

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Colibactin genes are highly prevalent in the developing infant gut microbiome.
Shira Levy, Kathryn E McCauley, Rachel Strength, Emily S Robbins, Qing Chen

Gut Microbes· December 2025

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Parthenolide Mitigates Doxorubicin-Induced Cardiotoxicity in Rats With Associated Activation of Nrf2 and Inhibition of Ferroptosis.
Jiayu Sun, Lei Qian, Feijie Guo, Fengjuan Gai, Peilin Lin

J Biochem Mol Toxicol· December 2025

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Tolerability, Safety, and Pharmacokinetics of Ivermectin After Nasal Application in Healthy Adult Subjects.
Stefan Wissel, Philipp Wissel, Matthias Rischer, Felix Häberlein, Hilde Riethmüller-Winzen

J Clin Pharmacol· January 2026

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Flash-Flow Generation and Selective Monoaddition of Organo-Potassium Species to Lactones.
Dong-Eun Yoo, Kazuhiro Okamoto, Manato Takeda, Hiroki Nakayama, Ruka Ebisawa

ChemSusChem· December 2025

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Transforming Amino Acids into Serotonin 5-HT Receptor Ligands Using Photochemistry.
Joseph O S Beckett, Ryan Buzdygon, Steven Nguyen, Allison A Clark, Serena S Schalk

J Am Chem Soc· December 2025

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GbSAUR48 regulates root development and terpenoid biosynthesis in Ginkgo biloba.
Jiawen Cui, Run Cui, Hongyan Bao, Yinuo Mao, Zhaogeng Lu

Tree Physiol· December 2025

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