43,687 results match your criteria: "Cellular Senescence"

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Benefits of Metformin in Attenuating the Hallmarks of Aging.
Ameya S Kulkarni, Sriram Gubbi, Nir Barzilai

July 2020

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mTOR as a central regulator of lifespan and aging.
David Papadopoli, Karine Boulay, Lawrence Kazak, Michael Pollak, Frédérick A Mallette

F1000Res· June 2020

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Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression.
Yao Dang, Yongpan An, Jinzhao He, Boyue Huang, Jie Zhu

January 2020

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Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial.
Christina Lee Chung, Ibiyonu Lawrence, Melissa Hoffman, Dareen Elgindi, Kumar Nadhan

December 2019

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Effect of tobacco smoking on the epigenetic age of human respiratory organs.
Xiaohui Wu, Qingsheng Huang, Ruheena Javed, Jiayong Zhong, Huan Gao

December 2019

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Proteostasis collapse is a driver of cell aging and death.
Mantu Santra, Ken A Dill, Adam M R de Graff

October 2019

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The mTORC1-autophagy pathway is a target for senescent cell elimination.
Olena Kucheryavenko, Glyn Nelson, Thomas von Zglinicki, Viktor I Korolchuk, Bernadette Carroll

Biogerontology· June 2019

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Senolytics and senostatics as adjuvant tumour therapy.
Susan Short, Edward Fielder, Satomi Miwa, Thomas von Zglinicki

EBioMedicine· March 2019

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RanGAP-mediated nucleocytoplasmic transport of Prospero regulates neural stem cell lifespan in Drosophila larval central brain.
Di Wu, Litao Wu, Huanping An, Hongcun Bao, Pengfei Guo

Aging Cell· February 2019

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mTOR as Regulator of Lifespan, Aging, and Cellular Senescence: A Mini-Review.
Thomas Weichhart

Gerontology· November 2018

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Fisetin is a senotherapeutic that extends health and lifespan.
Matthew J Yousefzadeh, Yi Zhu, Sara J McGowan, Luise Angelini, Heike Fuhrmann-Stroissnigg

October 2018

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Space radiation triggers persistent stress response, increases senescent signaling, and decreases cell migration in mouse intestine.
Santosh Kumar, Shubhankar Suman, Albert J Fornace, Kamal Datta

Proc Natl Acad Sci U S A· October 2018

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Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer

August 2018

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Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence.
Eva Latorre, Vishal C Birar, Angela N Sheerin, J Charles C Jeynes, Amy Hooper

October 2017

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The Clinical Potential of Senolytic Drugs.
James L Kirkland, Tamara Tchkonia, Yi Zhu, Laura J Niedernhofer, Paul D Robbins

J Am Geriatr Soc· October 2017

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p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli.
Brandon M Hall, Vitaly Balan, Anatoli S Gleiberman, Evguenia Strom, Peter Krasnov

Aging (Albany NY)· August 2017

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Biological Age Predictors.
Juulia Jylhävä, Nancy L Pedersen, Sara Hägg

EBioMedicine· July 2017

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Cellular Senescence: A Translational Perspective.
James L Kirkland, Tamara Tchkonia

EBioMedicine· July 2017

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Anti-Aging Potentials of Methylene Blue for Human Skin Longevity.
Zheng-Mei Xiong, Mike O'Donovan, Linlin Sun, Ji Young Choi, Margaret Ren

Sci Rep· May 2017

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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Marjolein P Baar, Renata M C Brandt, Diana A Putavet, Julian D D Klein, Kasper W J Derks

Cell· March 2017

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Proton Pump Inhibitors Accelerate Endothelial Senescence.
Gautham Yepuri, Roman Sukhovershin, Timo Z Nazari-Shafti, Michael Petrascheck, Yohannes T Ghebre

Circ Res· June 2016

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NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.
Hongbo Zhang, Dongryeol Ryu, Yibo Wu, Karim Gariani, Xu Wang

June 2016

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The Mitochondrial Basis of Aging.
Nuo Sun, Richard J Youle, Toren Finkel

Mol Cell· March 2016

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Delay discounting, genetic sensitivity, and leukocyte telomere length.
Onn-Siong Yim, Xing Zhang, Idan Shalev, Mikhail Monakhov, Songfa Zhong

March 2016

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Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians.
Yasumichi Arai, Carmen M Martin-Ruiz, Michiyo Takayama, Yukiko Abe, Toru Takebayashi

EBioMedicine· October 2015

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Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism.
Xing-Tai Li, Ya-Kui Zhang, Hai-Xue Kuang, Feng-Xin Jin, De-Wen Liu

September 2015

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding

Aging Cell· August 2015

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Multi-omics analysis reveals diagnostic and therapeutic biomarkers for aging phenotypes in ulcerative colitis.
Lei Guo, Jun Ge, Li Cheng, Xinyi Zhang, Zhengzheng Wu

PLoS One· December 2025

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Biological age threshold is associated with symptomatic knee osteoarthritis risk in chinese adults: Insights from machine learning analysis of a national cohort.
Fanyu Fu, Li Dong, Jiwei Lian, Chang Liu, Tingting Pang

PLoS One· December 2025

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RLX-201, a Novel mTORC1 Inhibitor With Potential to Promote Skin Longevity and Cellular Health.
Manpreet Randhawa, Krzysztof Bojanowski, Teresa Ferraro, Zhen Fang Huang Cao, Doris Day

Dermatol Surg· September 2025

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Integrated Bioinformatic Analysis and Experimental Validation for Crosstalk Among Various Forms of Cell Death in Spinal Cord Injury.
Kuileung Tong, Jianfeng Li, Shan Li, Shiming Li, Guoliang Chen

Mol Neurobiol· December 2025

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Endothelial Dysfunction Contributes to Chondrocyte Senescence Associated With Insulin-Like Growth Factor-Binding Protein-6 in a Spontaneously Hypertensive Rat Model.
Yuqi Zhang, Karen Ching, Lanlan Zhang, Lin Zhu, Siu Ling Yip

J Am Heart Assoc· December 2025

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Stem cells and ageing in the blood: an interview with Margaret (Peggy) Goodell.
Margaret Peggy Goodell

Dis Model Mech· December 2025

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Shortened telomere length, anxiety and psychological stress in systemic lupus erythematosus: a cross-sectional study.
Anna Carolina Faria Moreira Gomes Tavares, Carolina Ruas Freire Santos, Jéssica Martins Amaral, Ivonne Carolina Bolaños Burgos, Daniela Valadão Freitas Rosa

Adv Rheumatol· December 2025

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Mitochondrial dysfunction in cellular senescence: a bridge to neurodegenerative disease.
Adam J Hruby, Ryo Higuchi-Sanabria

NPJ Aging· December 2025

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Sympathetic-parasympathetic system deregulation theory of aging.
Joseph P Errico, Benneth Ben-Azu, Makenna Gargus, M Karen Newell Rogers, Marie-Ève Tremblay

NPJ Aging· December 2025

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[CHK1 attenuates cardiac senescence of mice through activating Rap1/Nox4 mediated oxidative stress homeostasis].
P Jing, L H Zhou, Y X Chen, L F Gu, C Du

Zhonghua Xin Xue Guan Bing Za Zhi· December 2025

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Associations between serum pigment epithelium-derived factor and physical performance in older women: The Otassha study.
Hiromichi Tsushima, Takashi Shida, Sho Hatanaka, Takahisa Ohta, Narumi Kojima

PLoS One· December 2025

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Pineal gland senescence: an emerging ageing-related pathology?
Emma Short, Ramzi Ajjan, Thomas M Barber, Sunil Bhandari, Paul Chazot

Hormones (Athens)· December 2025

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New Perspectives on Gastric Inflammaging: Integrating Multi-Omics Mechanisms and Gerotherapeutic Strategies in Chronic Gastritis.
Li Wang, Qiuye Chen, Houyan Zhang, Xin Zhao, Jinsheng Dong

Aging Dis· December 2025

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The regulatory networks and mechanisms of bone microenvironment in tumorigenesis and metastasis.
Guofang Huang, Tianhui Hou, Dianwen Song, Tong Meng

J Bone Oncol· December 2025

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Role of Circular RNAs in Liver Diseases.
Badr Alzahrani

Int J Med Sci· December 2025

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Targeted chelation therapy decreases NLRP3 expression by vascular cells and acts as senomorphic in chronic kidney disorder induced vascular calcification.
Shivani Arora, Gregory Halsey, Fatema Tuj Zohora, Alyssa Swiss, Narendra Vyavahare

Int J Immunopathol Pharmacol· December 2025

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Adenosine and guanosine-based oligonucleotides-loaded PLGA nanoparticles attenuates progression of surgically induced osteoarthritis.
Yoonhee Kim, Jin Han, Ji Young Park, Seungwoo Han

Drug Deliv Transl Res· December 2025

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Persistent pneumococcal colonisation in antiretroviral-treated HIV infection is associated with nasal inflammation.
Joseph Aston Phiri, Lusako Lucky Sibale, Gloria Kapira, Lukerensia Mlogoti, James Tchado Nyirenda

Nat Commun· December 2025

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Phosphorylation of CBX8 by PKD1 suppresses PRC1 activity and promotes cell senescence.
Zhiqiang Fang, Doudou Liu, Yuanyuan Su, Fengxin Hao, Ruodong Qin

Oncogene· December 2025

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Mitochondrial RNA cytosolic leakage drives the SASP.
Stella Victorelli, Madeline Eppard, Hélène Martini, Seung-Hwa Woo, Stacia P A Everts

Nat Commun· December 2025

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Long-term high-protein diet intake accelerates adipocyte senescence through macrophage CD38-mediated NAD depletion.
Xiaohan Yang, Lun Hua, Dengfeng Gao, Yanni Wu, Yi Yang

Mol Metab· December 2025

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AnnoTCM: An Annotation Tool for Multimodal Metabolite-Phenotype Integration in Decoding Bioactive Compounds of Traditional Chinese Medicine.
Xingyi Liang, Yixin Cui, Yanwei Tan, Yang Zhou, Xingzu Cao

Anal Chem· December 2025

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α7 Nicotinic acetylcholine receptor activation rescues mitochondrial dysfunction in gestational diabetes mellitus by competing with p66Shc for VDAC1 binding.
Lulu Ji, Yaru Nai, Zhiguo Chen, Yu Zhong, Hengxuan Zhu

Diabetologia· December 2025

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Mammary Fibroblasts Secrete Damage Associated Molecular Patterns through Extracellular Vesicles in Response to Ionizing Radiation.
Greg Berumen Sánchez, Purvi Patel, Preston Gomez-Crase, Chloe Kim, Kristie Lindsey Rose

bioRxiv· November 2025

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Uncovering senescent fibroblast heterogeneity connects DNA damage response to idiopathic pulmonary fibrosis.
Jun-Wei B Hughes, Akshay Pujari, Anja Sandholm, Duncan Croll, Lea B Monk

bioRxiv· November 2025

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Chronic cervical instability in mice and rats: a reproducible model to simulate human intervertebral disc degeneration.
Kewu Tu, Junhao Tan, Guanhai Zeng, Fuzhou Xu, Dongteng Liao

PeerJ· December 2025

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The impact of cellular senescence on aging skeletal muscle.
Michael Kamal, Ryan Bevington, Amanda Johnson, Gianni Parise

Front Cell Dev Biol· December 2025

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