Urocanase-Positive Skin-Resident Bacteria Metabolize cis-Urocanic Acid and in Turn Reduce the Immunosuppressive Properties of UVR.
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Disease Models Animal
246 articles with social media discussions tracked by PubHawk in this topic.
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Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3.
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Lithium deficiency and the onset of Alzheimer's disease.
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An mRNA-based broad-spectrum antiviral inspired by ISG15 deficiency protects against viral infections in vitro and in vivo.
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Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice.
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Post-stress modulation of the HPA and melanocortin systems alleviates migraine-like behaviors in mice.
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Distinct systemic impacts of Aβ42 and Tau revealed by whole-organism snRNA-seq.
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Immunotherapy-related cognitive impairment after CAR T cell therapy in mice.
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Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer.
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Global changes in virulence and metabolism during colonization of healthy skin.
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Neoadjuvant intratumoral MBT(A) immunotherapy prevents distant metastases and recurrence in murine models.
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Senolytic treatment for low back pain.
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Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration.
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Development of a new antibody drug to treat congenital tooth agenesis.
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Hair-straightening cosmetics containing glyoxylic acid induce crystalline nephropathy.
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Glyphosate exposure exacerbates neuroinflammation and Alzheimer's disease-like pathology despite a 6-month recovery period in mice.
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Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice.
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Disrupted Human-Dog Interbrain Neural Coupling in Autism-Associated Shank3 Mutant Dogs.
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Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease.
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Bone-marrow macrophage-derived GPNMB protein binds to orphan receptor GPR39 and plays a critical role in cardiac repair.
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Lipidized analogues of the anorexigenic CART (cocaine- and amphetamine-regulated transcript) neuropeptide show anorexigenic and neuroprotective potential in mouse model of monosodium-glutamate induced obesity.
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Food antigens suppress small intestinal tumorigenesis.
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Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury.
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Reduction of myeloid-derived suppressor cells in prostate cancer murine models and patients following white button mushroom treatment.
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