581,056 results match your criteria: "Disease Models Animal"

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Urocanase-Positive Skin-Resident Bacteria Metabolize cis-Urocanic Acid and in Turn Reduce the Immunosuppressive Properties of UVR.
VijayKumar Patra, Slave Trajanoski, Aaroh Joshi, Vanina Lenief, Chloe Goyet

J Invest Dermatol· November 2025

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Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3.
Pavlos Ioannou, Christoforos Odiatis, Rania Hadjisavva, Kyriaki Antoniadou, Myrtani Pieri

Kidney Int· October 2025

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Lithium deficiency and the onset of Alzheimer's disease.
Liviu Aron, Zhen Kai Ngian, Chenxi Qiu, Jaejoon Choi, Marianna Liang

Nature· September 2025

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An mRNA-based broad-spectrum antiviral inspired by ISG15 deficiency protects against viral infections in vitro and in vivo.
Yemsratch T Akalu, Roosheel S Patel, Justin Taft, Rodrigo Canas-Arranz, Rachel Geltman

August 2025

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Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice.
Marisa Ferreira-Marques, Sara Carmo-Silva, Joana Pereira, Mariana Botelho, Clévio Nóbrega

Geroscience· August 2025

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Post-stress modulation of the HPA and melanocortin systems alleviates migraine-like behaviors in mice.
Ya-Yu Hu, Hao-Ruei Mei, Shruti Sankar, Abbas Pirwani, Armen Akopian

Cephalalgia· July 2025

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Distinct systemic impacts of Aβ42 and Tau revealed by whole-organism snRNA-seq.
Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, Lindsey D Goodman, Lindsey Ran

Neuron· July 2025

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Immunotherapy-related cognitive impairment after CAR T cell therapy in mice.
Anna C Geraghty, Lehi Acosta-Alvarez, Maria C Rotiroti, Selena Dutton, Michael R O'Dea

Cell· June 2025

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Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer.
Bhupesh Kumar Thakur, Yann Malaise, Saurav Roy Choudhury, Anna Neustaeter, Williams Turpin

Nat Microbiol· April 2025

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Global changes in virulence and metabolism during colonization of healthy skin.
Timothy J Enroth, Morgan M Severn, Flavia G Costa, Alyson R Bovee, Reid V Wilkening

April 2025

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Neoadjuvant intratumoral MBT(A) immunotherapy prevents distant metastases and recurrence in murine models.
Ondrej Uher, Katerina Hadrava Vanova, Rachael Labitt, Katerina Petrlakova, Juan Ye

March 2025

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Senolytic treatment for low back pain.
Matthew Mannarino, Hosni Cherif, Saber Ghazizadeh, Oliver Wu Martinez, Kai Sheng

Sci Adv· March 2025

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Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration.
Mara Bouwman, Dennis E M de Bakker, Hessel Honkoop, Alexandra E Giovou, Danielle Versteeg

Nat Cardiovasc Res· January 2025

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Development of a new antibody drug to treat congenital tooth agenesis.
K Takahashi, H Kiso, E Mihara, J Takagi, Y Tokita

J Oral Biosci· December 2024

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2 75 2 10

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Hair-straightening cosmetics containing glyoxylic acid induce crystalline nephropathy.
Thomas Robert, Ellie Tang, Jennifer Kervadec, Aurore Desmons, Jean-Yves Hautem

Kidney Int· December 2024

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2 3 2 129 3

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Glyphosate exposure exacerbates neuroinflammation and Alzheimer's disease-like pathology despite a 6-month recovery period in mice.
Samantha K Bartholomew, Wendy Winslow, Ritin Sharma, Khyatiben V Pathak, Savannah Tallino

J Neuroinflammation· December 2024

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Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice.
Victor Fattori, Tiago H Zaninelli, Fernanda S Rasquel-Oliveira, Olivia K Heintz, Ashish Jain

Sci Transl Med· November 2024

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Disrupted Human-Dog Interbrain Neural Coupling in Autism-Associated Shank3 Mutant Dogs.
Wei Ren, Shan Yu, Kun Guo, Chunming Lu, Yong Q Zhang

November 2024

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Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease.
Leelavathi N Madhu, Maheedhar Kodali, Raghavendra Upadhya, Shama Rao, Yogish Somayaji

J Extracell Vesicles· November 2024

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Bone-marrow macrophage-derived GPNMB protein binds to orphan receptor GPR39 and plays a critical role in cardiac repair.
Sivakumar Ramadoss, Juan Qin, Bo Tao, Nathan E Thomas, Edward Cao

Nat Cardiovasc Res· November 2024

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Lipidized analogues of the anorexigenic CART (cocaine- and amphetamine-regulated transcript) neuropeptide show anorexigenic and neuroprotective potential in mouse model of monosodium-glutamate induced obesity.
Vilém Charvát, Anna Strnadová, Aneta Myšková, David Sýkora, Miroslava Blechová

Eur J Pharmacol· October 2024

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Food antigens suppress small intestinal tumorigenesis.
Takaharu Sasaki, Yuna Ota, Yui Takikawa, Tommy Terrooatea, Takashi Kanaya

Front Immunol· October 2024

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Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury.
Zhiyong Guo, Meixian Yin, Chengjun Sun, Guixing Xu, Tielong Wang

EMBO Mol Med· October 2024

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Reduction of myeloid-derived suppressor cells in prostate cancer murine models and patients following white button mushroom treatment.
Xiaoqiang Wang, Shoubao Ma, Przemyslaw Twardowski, Clayton Lau, Yin S Chan

October 2024

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Antibiotics damage the colonic mucus barrier in a microbiota-independent manner.
Jasmin Sawaed, Lilach Zelik, Yehonatan Levin, Rachel Feeney, Maria Naama

September 2024

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2 7 4 145 6 32 3

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Inhibition of colorectal cancer in Alzheimer's disease is mediated by gut microbiota via induction of inflammatory tolerance.
Nan Zhang, Rui Zhang, Lei Jiang, Zhaoyu Gao, Wenzhen Xia

September 2024

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Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids.
Jiaxiang Wu, Jingliang Zhang, Xiaoling Chen, Kyle Wettschurack, Zhefu Que

Mol Psychiatry· August 2024

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Programming fetal cardiometabolic pathways: the double-edged role of glucocorticoids in heart development.
Reza Amanollahi, Melanie Bertossa, Kent Thornburg, Michael Wiese, Mitchell Lock

J Dev Orig Health Dis· December 2025

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[Hippocampal stereotactic injection of cerebrospinal fluid from single-prolonged stress mice induces PTSD-like behavior].
Ke-Ke Ding, Dao-Kang Chen, Shao-Jie Yang, Guo-Qi Zhu

Sheng Li Xue Bao· December 2025

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[Research progress on the role of miR-132 in the pathogenesis of depression].
Ding-Lun Meng, Qing-Yan Wang, Xin Zhang, Shu-Hong Li, Chun-Ping Tian

Sheng Li Xue Bao· December 2025

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Identification of coilin in bone marrow as a potential neuroblastoma tumor progression marker transcriptionally regulated by MYCN.
Zhixia Yue, Lan Li, Shuguang Liu, Chao Gao, Sidou He

Cancer Biol Ther· December 2026

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Cortical layer multi-parameter analysis of neurovascular impairments in AD/ADRD rodent model with in vivo optical imaging.
Hyomin Jeong, Jiaxiang Ren, Wensheng Cheng, Nora D Volkow, Haibin Ling

Transl Neurodegener· December 2025

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Chromatin remodeling factor BAF155 coordinates oligodendroglial-neuronal communications linked to regional myelination and autism-like behavioral deficits in mice.
Xiaorui Wang, Cong Zeng, Zhonghao Wu, Minmin Lu, Xiao Wang

Nat Commun· December 2025

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Isochlorogenic Acid C and Extract Prevent Acute Gastritis by Mitigating Gastric Mucosa Injury and Mitochondrial Dysfunction.
So Jeong Paik, Hai-Hua Jiang, Sang-Ho Lee, Eun-Hye Han, Na-Young Yun

J Microbiol Biotechnol· December 2025

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Cannabigerol Exerts and Anti-Inflammatory Effects via Inhibition of the MAPK and NF-κB Pathways.
Jong-Hui Kim, Min Hong, Joon-Hee Han, Byeong Ryeol Ryu, Jung Dae Lim

J Microbiol Biotechnol· December 2025

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TGF-βRII/IL-15 immunotherapeutic complex targets exhausted CD8 T-cell subsets in lymph nodes and tumors.
Varghese K George, Hing C Wong, Martin Felices, Mark P Rubinstein, Niraj Shrestha

J Immunother Cancer· December 2025

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Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration.
Sivakumar Srinivasan, Christian Pifl, Thomas Steinkellner

Br J Pharmacol· December 2025

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Menstrual cycles, lifespan, and anti-Müllerian hormone in cynomolgus monkeys.
Akie Takebayashi, Shunichiro Tsuji, Tadashi Sankai, Chizuru Iwatani, Hideaki Tsuchiya

Exp Anim· December 2025

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Longitudinal brain-wide recordings reveal early neurophysiological alterations in memory-impaired mice.
Abdelrahman B M Eldaly, Stephen K Agadagba, Antara Verma, Kongyan Li, Lee Wei Lim

Neuroscience· December 2025

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In Vitro Expansion of Dendritic Cells Pulsed with Placental Peptides for the Generation of Antigen-Specific T Cells with Antitumor Activity.
Yu Lin, NengPing Huang, YuanBin He, PengJu Zuo, LiQiu Yang

Iran J Immunol· December 2025

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Targeting secreted PLA interactions with EGFR and vimentin to arrest prostate tumour growth.
Timothy J Mann, Ryung Rae Kim, Mila Sajinovic, Shadma Fatima, Vinod Kumar

Cell Death Dis· December 2025

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Dracorhodin Perchlorate Targets SrtA To Alleviate Staphylococcus Aureus Pneumonia Infection in Vitro and in Vivo.
Chenyi Zhang, Chunhua Li, Haiyang Wang, Cuiqing Zhao, Yumin Liu

Curr Microbiol· December 2025

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Modeling pathogenesis and progression of metabolic dysfunction-associated steatotic liver disease and therapeutic drug screening using hESC-derived mature polarized hepatocyte organoids.
Changlu Qin, Haibin Wu, Peilin Liao, Wenjiao Yan, Xinyi Shi

Stem Cell Res Ther· December 2025

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Multi-target neuroprotective effects of notoginsenoside R1 in neurodegenerative diseases: From pharmacokinetics to translational prospects.
Hao-Wen Lin, Shi-Pian Li, Jia-Xin Wen, Jia-Xuan Zhang, Bi-Meng Zhang

Pharmacol Res· December 2025

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Microplastic and nanoplastic pollution and associated potential disease risks.
Nurshad Ali, Jenny Katsouli, Eric Auyang, Jorge Bernardino de la Serna

Lancet Planet Health· December 2025

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KuiAnNingFang alleviates ulcerative colitis by modulating gut microbiota and NF-κB/NLRP3 pathway.
Chunli Sun, Yuehuan Tian, Yitan Zheng, Kunrong Yang, Shengnan Liu

Phytomedicine· December 2025

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Piceatannol as a multi-target neuroprotective agent: mechanistic insights and therapeutic prospects in neurological disorders.
Arif Hossain, Emon Mia, Sakib Al Hasan, Mohammad Y Alshahrani, Asmaul Husna Bristy

Metab Brain Dis· December 2025

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Exploring the Neuroprotective Role of the Sulfonamide Derivative KM11 in Ethidium Bromide-induced Demyelination in Zebrafish Model Through Modulation of Antioxidant and Inflammatory Cytokine Pathways.
Karthikeyan Ramamurthy, Magesh Santhanakrishnan, S Madesh, Prasannakumar Raja, Senthilkumar Palaniappan

Mol Neurobiol· December 2025

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Clinical validation of T1ρ mapping for the assessment of hepatic fibrosis in patients with chronic liver disease.
Narine Mesropyan, Johannes Chang, Philipp Lutz, Felix Kaiser, Oliver M Weber

Eur Radiol· December 2025

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Fasted-State Aerobic Exercise Enhances Cognition and Hippocampal BDNF Signaling in an Alzheimer's Disease Rat Model.
Fatih Kirkbir, Taner Atasoy, Davar Khodadadai, Heidar Sajedi, Ozlem Keskin

Neurochem Res· December 2025

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Zebrafish as a new approach methodology (NAM) in dermatology: current research and the regulatory landscape focusing on sustainable development goals.
Sourik Mukherjee, Aman Kumar Mohanty, Abhijit Poddar

Acta Dermatovenerol Alp Pannonica Adriat· December 2025

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Natural Compounds as Nephroprotective Agents: Therapeutic Potential Against Drug-Induced Kidney Injury.
Mukul Shyam, Abantika Pal, Dishari Dey, Kiruba J, Vidhi Sharma

J Biochem Mol Toxicol· December 2025

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Therapeutic potential of curcumin in ophthalmic diseases: mechanisms and clinical applications.
Kangning Wang, Tian Tian, Zijian Chen, Xue He, Yi Xiang

J Transl Med· December 2025

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PET imaging of cardiac sympathetic nervous system dysfunction using meta-[F]fluorobenzylguanidine.
Uzair S Ismailani, Ariel Buchler, Jadde de Carvalho Tso, Serena M Pulente, Faduma Abdirahman

Eur J Nucl Med Mol Imaging· December 2025

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